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Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology.

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Title: Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology.
Authors: Gödicke S; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center, Hamburg-Eppendorf, Hamburg, Germany., Kresbach C; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center, Hamburg-Eppendorf, Hamburg, Germany.; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany., Ehlert M; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center, Hamburg-Eppendorf, Hamburg, Germany., Obrecht D; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Altendorf L; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center, Hamburg-Eppendorf, Hamburg, Germany., Hack K; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center, Hamburg-Eppendorf, Hamburg, Germany., von Hoff K; Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Berlin Institute of Health, Berlin, Germany.; Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark., Carén H; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Center for Cancer Research, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden., Melcher V; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, 48149, Münster, Germany., Kerl K; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, 48149, Münster, Germany., Englinger B; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, 1090, Vienna, Austria.; Center for Cancer Research and Comprehensive Cancer Center, Medical University Vienna, 1090, Vienna, Austria., Filbin M; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA., Pajtler KW; Hopp Children's Cancer Center Heidelberg (KiTZ), 69120, Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), 69120, Heidelberg, Germany.; Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, 69120, Heidelberg, Germany., Gojo J; Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics and Comprehensive Cancer Center, Medical University of Vienna, 1090, Vienna, Austria., Pietsch T; Institute of Neuropathology, DGNN Brain Tumor Reference Center, University of Bonn Medical Center, Bonn, Germany., Rutkowski S; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Schüller U; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. u.schueller@uke.de.; Research Institute Children's Cancer Center, Hamburg-Eppendorf, Hamburg, Germany. u.schueller@uke.de.; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. u.schueller@uke.de.
Source: Acta neuropathologica [Acta Neuropathol] 2024 Jan 24; Vol. 147 (1), pp. 23. Date of Electronic Publication: 2024 Jan 24.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology.
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  Data: <searchLink fieldCode="AU" term="%22Gödicke+S%22">Gödicke S</searchLink>; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center, Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kresbach+C%22">Kresbach C</searchLink>; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center, Hamburg-Eppendorf, Hamburg, Germany.; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ehlert+M%22">Ehlert M</searchLink>; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center, Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Obrecht+D%22">Obrecht D</searchLink>; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Altendorf+L%22">Altendorf L</searchLink>; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center, Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hack+K%22">Hack K</searchLink>; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center, Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22von+Hoff+K%22">von Hoff K</searchLink>; Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Berlin Institute of Health, Berlin, Germany.; Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Carén+H%22">Carén H</searchLink>; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Center for Cancer Research, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.<br /><searchLink fieldCode="AU" term="%22Melcher+V%22">Melcher V</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, 48149, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Kerl+K%22">Kerl K</searchLink>; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, 48149, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Englinger+B%22">Englinger B</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, 1090, Vienna, Austria.; Center for Cancer Research and Comprehensive Cancer Center, Medical University Vienna, 1090, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Filbin+M%22">Filbin M</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.<br /><searchLink fieldCode="AU" term="%22Pajtler+KW%22">Pajtler KW</searchLink>; Hopp Children's Cancer Center Heidelberg (KiTZ), 69120, Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), 69120, Heidelberg, Germany.; Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, 69120, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Gojo+J%22">Gojo J</searchLink>; Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics and Comprehensive Cancer Center, Medical University of Vienna, 1090, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Pietsch+T%22">Pietsch T</searchLink>; Institute of Neuropathology, DGNN Brain Tumor Reference Center, University of Bonn Medical Center, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Rutkowski+S%22">Rutkowski S</searchLink>; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schüller+U%22">Schüller U</searchLink>; Department of Pediatric Hematolgoy and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. u.schueller@uke.de.; Research Institute Children's Cancer Center, Hamburg-Eppendorf, Hamburg, Germany. u.schueller@uke.de.; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. u.schueller@uke.de.
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  Data: <searchLink fieldCode="JN" term="%220412041%22">Acta neuropathologica</searchLink> [Acta Neuropathol] 2024 Jan 24; Vol. 147 (1), pp. 23. <i>Date of Electronic Publication: </i>2024 Jan 24.
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