The rare DRB1*04:08-DQ8 haplotype is the main HLA class II genetic driver and discriminative factor of Early-onset Type 1 diabetes in the Portuguese population.

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Title:	The rare DRB1*04:08-DQ8 haplotype is the main HLA class II genetic driver and discriminative factor of Early-onset Type 1 diabetes in the Portuguese population.
Authors:	Caramalho I; Instituto Gulbenkian de Ciência, Oeiras, Portugal.; Faculdade de Ciências, Universidade de Lisboa, Lisboa, Portugal., Matoso P; Instituto Gulbenkian de Ciência, Oeiras, Portugal., Ligeiro D; Centro de Sangue e Transplantação de Lisboa, Instituto Português do Sangue e Transplantação, Unidade de Imunocirurgia e Imunoterapia, Fundação Champalimaud, Lisboa, Portugal., Paixão T; Instituto Gulbenkian de Ciência, Oeiras, Portugal., Sobral D; Instituto Gulbenkian de Ciência, Oeiras, Portugal., Fitas AL; Pediatric Endocrinology Unit, Hospital de Dona Estefânia, Centro Hospitalar Universitário de Lisboa Central (CHULC)/Nova Medical School, Lisbon, Portugal., Limbert C; Pediatric Endocrinology Unit, Hospital de Dona Estefânia, Centro Hospitalar Universitário de Lisboa Central (CHULC)/Nova Medical School, Lisbon, Portugal.; Comprehensive Health Research Centre (CHRC), NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal., Demengeot J; Instituto Gulbenkian de Ciência, Oeiras, Portugal., Penha-Gonçalves C; Instituto Gulbenkian de Ciência, Oeiras, Portugal.
Source:	Frontiers in immunology [Front Immunol] 2024 Jan 03; Vol. 14, pp. 1299609. Date of Electronic Publication: 2024 Jan 03 (Print Publication: 2023).
Publication Type:	Journal Article; Research Support, Non-U.S. Gov't
Journal Info:	Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database:	MEDLINE Ultimate

Description
ISSN:	1664-3224
DOI:	10.3389/fimmu.2023.1299609