IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy.

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Title: IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy.
Authors: Tanner G; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Barrow R; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Ajaib S; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Al-Jabri M; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Ahmed N; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Pollock S; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Finetti M; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Rippaus N; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Bruns AF; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK., Syed K; The Walton Centre NHS Foundation Trust, Liverpool, UK., Poulter JA; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Matthews L; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Hughes T; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.; School of Science, Technology and Health, York St John University, York, YO31 7EX, UK., Wilson E; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Johnson C; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Varn FS; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Brüning-Richardson A; School of Applied Sciences, University of Huddersfield, Huddersfield, UK., Hogg C; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Droop A; Welcome Sanger Institute, Hinxton, Saffron Walden, UK., Gusnanto A; School of Mathematics, University of Leeds, Leeds, UK., Care MA; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Cutillo L; School of Mathematics, University of Leeds, Leeds, UK., Westhead DR; School of Molecular and Cellular Biology, University of Leeds, Leeds, UK., Short SC; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.; Leeds Teaching Hospital, Leeds, UK., Jenkinson MD; The Walton Centre NHS Foundation Trust, Liverpool, UK.; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Brodbelt A; The Walton Centre NHS Foundation Trust, Liverpool, UK., Chakrabarty A; Leeds Teaching Hospital, Leeds, UK., Ismail A; Leeds Teaching Hospital, Leeds, UK., Verhaak RGW; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Yale School of Medicine, New Haven, CT, USA., Stead LF; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK. l.f.stead@leeds.ac.uk.
Source: Genome biology [Genome Biol] 2024 Feb 07; Vol. 25 (1), pp. 45. Date of Electronic Publication: 2024 Feb 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1474-760X
DOI:10.1186/s13059-024-03172-3