Same-day versus rapid ART initiation in HIV-positive individuals presenting with symptoms of tuberculosis: Protocol for an open-label randomized non-inferiority trial in Lesotho and Malawi.

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Title: Same-day versus rapid ART initiation in HIV-positive individuals presenting with symptoms of tuberculosis: Protocol for an open-label randomized non-inferiority trial in Lesotho and Malawi.
Authors: Gerber F; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Semphere R; Helse Nord Tuberculosis Initiative, Kamuzu University of Health Sciences, Blantyre, Malawi., Lukau B; SolidarMed Lesotho, Maseru, Lesotho., Mahlatsi P; SolidarMed Lesotho, Maseru, Lesotho., Mtenga T; Helse Nord Tuberculosis Initiative, Kamuzu University of Health Sciences, Blantyre, Malawi., Lee T; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland., Kohler M; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland., Glass TR; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Amstutz A; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland.; Oslo Center for Biostatistics and Epidemiology, Oslo University Hospital, University of Oslo, Oslo, Norway.; Bristol Medical School, University of Bristol, Bristol, United Kingdom., Molatelle M; Seboche Mission Hospital Laboratory, Seboche, Lesotho., MacPherson P; School of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom., Marake NB; Ministry of Health Lesotho, Maseru, Lesotho., Nliwasa M; Helse Nord Tuberculosis Initiative, Kamuzu University of Health Sciences, Blantyre, Malawi.; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi., Ayakaka I; SolidarMed Lesotho, Maseru, Lesotho., Burke R; London School of Hygiene and Tropical Medicine, London, United Kingdom., Labhardt N; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; University of Basel, Basel, Switzerland.
Source: PloS one [PLoS One] 2024 Feb 08; Vol. 19 (2), pp. e0288944. Date of Electronic Publication: 2024 Feb 08 (Print Publication: 2024).
Publication Type: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0288944