The small molecule raptinal can simultaneously induce apoptosis and inhibit PANX1 activity.
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| Title: | The small molecule raptinal can simultaneously induce apoptosis and inhibit PANX1 activity. |
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| Authors: | Santavanond JP; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia.; Research Centre of Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia., Chiu YH; Departments of Medical Science, Life Science, and Medicine, National Tsing Hua University, Hsinchu, Taiwan. yhchiu@life.nthu.edu.tw.; Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan. yhchiu@life.nthu.edu.tw., Tixeira R; Unit for Cell Clearance in Health and Disease, VIB Center for Inflammation Research, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium., Liu Z; Immunology Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Yap JKY; Immunology Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Chen KW; Immunology Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Li CL; Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan., Lu YR; Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan., Roncero-Carol J; Regenerative Medicine Program, Bellvitge Institute for Biomedical Research (IDIBELL), Barcelona, Spain.; Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain., Hoijman E; Regenerative Medicine Program, Bellvitge Institute for Biomedical Research (IDIBELL), Barcelona, Spain.; Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain., Rutter SF; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia.; Research Centre of Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia., Shi B; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia.; Research Centre of Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia., Ryan GF; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia.; Research Centre of Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia., Hodge AL; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia.; Research Centre of Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia., Caruso S; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia.; Research Centre of Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia., Baxter AA; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia.; Research Centre of Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia., Ozkocak DC; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia.; Research Centre of Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia., Johnson C; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia., Day ZI; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia., Mayfosh AJ; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia., Hulett MD; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia.; Research Centre of Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia., Phan TK; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia.; Research Centre of Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia.; The Walter and Eliza Hall Institute of Medial Research, Parkville, Vic, Australia., Atkin-Smith GK; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia.; Research Centre of Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia.; The Walter and Eliza Hall Institute of Medial Research, Parkville, Vic, Australia.; University of Melbourne, Melbourne, VIC, Australia., Poon IKH; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, 3086, Australia. i.poon@latrobe.edu.au.; Research Centre of Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia. i.poon@latrobe.edu.au. |
| Source: | Cell death & disease [Cell Death Dis] 2024 Feb 09; Vol. 15 (2), pp. 123. Date of Electronic Publication: 2024 Feb 09. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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