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Metal-free photocatalytic cross-electrophile coupling enables C1 homologation and alkylation of carboxylic acids with aldehydes.

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Title: Metal-free photocatalytic cross-electrophile coupling enables C1 homologation and alkylation of carboxylic acids with aldehydes.
Authors: Bonciolini S; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands., Pulcinella A; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands., Leone M; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands.; Institut de Chimie des Substances Naturelles, CNRS, Univ. Paris-Saclay, 1 Avenue de la Terrasse, 91198, Gif-sur-Yvette, Cedex, France., Schiroli D; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands.; SynCat Lab, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124, Parma, Italy., Ruiz AL; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands.; PhotoGreen Lab, Department of Chemistry, University of Pavia, 27100, Pavia, Italy., Sorato A; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands., Dubois MAJ; Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Gopalakrishnan R; Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Masson G; Institut de Chimie des Substances Naturelles, CNRS, Univ. Paris-Saclay, 1 Avenue de la Terrasse, 91198, Gif-sur-Yvette, Cedex, France., Della Ca' N; SynCat Lab, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124, Parma, Italy., Protti S; PhotoGreen Lab, Department of Chemistry, University of Pavia, 27100, Pavia, Italy., Fagnoni M; PhotoGreen Lab, Department of Chemistry, University of Pavia, 27100, Pavia, Italy., Zysman-Colman E; Organic Semiconductor Centre, EaStCHEM School of Chemistry, Purdie Building, North Haugh University of St Andrews, St Andrews, Fife, KY16 9ST, UK., Johansson M; Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Noël T; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands. t.noel@uva.nl.
Source: Nature communications [Nat Commun] 2024 Feb 19; Vol. 15 (1), pp. 1509. Date of Electronic Publication: 2024 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE; PubMed not MEDLINE
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  Data: Metal-free photocatalytic cross-electrophile coupling enables C1 homologation and alkylation of carboxylic acids with aldehydes.
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  Data: <searchLink fieldCode="AU" term="%22Bonciolini+S%22">Bonciolini S</searchLink>; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pulcinella+A%22">Pulcinella A</searchLink>; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Leone+M%22">Leone M</searchLink>; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands.; Institut de Chimie des Substances Naturelles, CNRS, Univ. Paris-Saclay, 1 Avenue de la Terrasse, 91198, Gif-sur-Yvette, Cedex, France.<br /><searchLink fieldCode="AU" term="%22Schiroli+D%22">Schiroli D</searchLink>; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands.; SynCat Lab, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Ruiz+AL%22">Ruiz AL</searchLink>; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands.; PhotoGreen Lab, Department of Chemistry, University of Pavia, 27100, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Sorato+A%22">Sorato A</searchLink>; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dubois+MAJ%22">Dubois MAJ</searchLink>; Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Gopalakrishnan+R%22">Gopalakrishnan R</searchLink>; Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Masson+G%22">Masson G</searchLink>; Institut de Chimie des Substances Naturelles, CNRS, Univ. Paris-Saclay, 1 Avenue de la Terrasse, 91198, Gif-sur-Yvette, Cedex, France.<br /><searchLink fieldCode="AU" term="%22Della+Ca'+N%22">Della Ca' N</searchLink>; SynCat Lab, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Protti+S%22">Protti S</searchLink>; PhotoGreen Lab, Department of Chemistry, University of Pavia, 27100, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Fagnoni+M%22">Fagnoni M</searchLink>; PhotoGreen Lab, Department of Chemistry, University of Pavia, 27100, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Zysman-Colman+E%22">Zysman-Colman E</searchLink>; Organic Semiconductor Centre, EaStCHEM School of Chemistry, Purdie Building, North Haugh University of St Andrews, St Andrews, Fife, KY16 9ST, UK.<br /><searchLink fieldCode="AU" term="%22Johansson+M%22">Johansson M</searchLink>; Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Noël+T%22">Noël T</searchLink>; Flow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098, XH Amsterdam, The Netherlands. t.noel@uva.nl.
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