Silencing Parkinson's risk allele Rit2 sex-specifically compromises motor function and dopamine neuron viability.
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| Title: | Silencing Parkinson's risk allele Rit2 sex-specifically compromises motor function and dopamine neuron viability. |
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| Authors: | Kearney PJ; Brudnick Neuropsychiatric Research Institute, Department of Neurobiology, UMASS Chan Medical School, Worcester, MA, USA.; Graduate Program in Neuroscience, Morningside Graduate School of Biomedical Sciences, UMass Chan Medical School, Worcester, MA, USA.; University of California, San Diego, CA, USA., Zhang Y; Department of Neurology and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Liang M; Department of Neurology and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Tan Y; Mass Spectrometry Facility, Department of Biochemistry and Molecular Biotechnology, UMASS Chan Medical School, Worcester, MA, USA.; DMPK Group, Merck, S. San Francisco, CA, USA., Kahuno E; Brudnick Neuropsychiatric Research Institute, Department of Neurobiology, UMASS Chan Medical School, Worcester, MA, USA., Conklin TL; Brudnick Neuropsychiatric Research Institute, Department of Neurobiology, UMASS Chan Medical School, Worcester, MA, USA.; Regeneron, Albany, NY, USA., Fagan RR; Brudnick Neuropsychiatric Research Institute, Department of Neurobiology, UMASS Chan Medical School, Worcester, MA, USA.; Graduate Program in Neuroscience, Morningside Graduate School of Biomedical Sciences, UMass Chan Medical School, Worcester, MA, USA.; University of California, San Francisco, CA, USA., Pavchinskiy RG; Brudnick Neuropsychiatric Research Institute, Department of Neurobiology, UMASS Chan Medical School, Worcester, MA, USA.; Graduate Program in Neuroscience, Morningside Graduate School of Biomedical Sciences, UMass Chan Medical School, Worcester, MA, USA., Shaffer SA; Mass Spectrometry Facility, Department of Biochemistry and Molecular Biotechnology, UMASS Chan Medical School, Worcester, MA, USA., Yue Z; Department of Neurology and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Melikian HE; Brudnick Neuropsychiatric Research Institute, Department of Neurobiology, UMASS Chan Medical School, Worcester, MA, USA. haley.melikian@umassmed.edu.; Graduate Program in Neuroscience, Morningside Graduate School of Biomedical Sciences, UMass Chan Medical School, Worcester, MA, USA. haley.melikian@umassmed.edu. |
| Source: | NPJ Parkinson's disease [NPJ Parkinsons Dis] 2024 Feb 23; Vol. 10 (1), pp. 41. Date of Electronic Publication: 2024 Feb 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2373-8057 |
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| DOI: | 10.1038/s41531-024-00648-8 |
