DNA and RNA base editors can correct the majority of pathogenic single nucleotide variants.

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Title: DNA and RNA base editors can correct the majority of pathogenic single nucleotide variants.
Authors: Dadush A; Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, Israel.; The Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat Gan, Israel., Merdler-Rabinowicz R; Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, Israel.; The Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat Gan, Israel.; Cancer Data Science Lab, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Gorelik D; Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, Israel.; The Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat Gan, Israel., Feiglin A; Skip Therapeutics Ltd, 2 Ilan Ramon St, Ness Ziona, Israel., Buchumenski I; Skip Therapeutics Ltd, 2 Ilan Ramon St, Ness Ziona, Israel., Pal LR; Cancer Data Science Lab, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Ben-Aroya S; Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, Israel., Ruppin E; Cancer Data Science Lab, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Levanon EY; Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, Israel. Erez.Levanon@biu.ac.il.; The Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat Gan, Israel. Erez.Levanon@biu.ac.il.
Source: NPJ genomic medicine [NPJ Genom Med] 2024 Feb 26; Vol. 9 (1), pp. 16. Date of Electronic Publication: 2024 Feb 26.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature in partnership with the Center of Excellence in Genomic Medicine Research at King Abdulaziz University Country of Publication: England NLM ID: 101685193 Publication Model: Electronic Cited Medium: Internet ISSN: 2056-7944 (Electronic) Linking ISSN: 20567944 NLM ISO Abbreviation: NPJ Genom Med Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2056-7944
DOI:10.1038/s41525-024-00397-w