G2019S selective LRRK2 kinase inhibitor abrogates mitochondrial DNA damage.

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Title: G2019S selective LRRK2 kinase inhibitor abrogates mitochondrial DNA damage.
Authors: Pena N; Departments of Neurology and Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, USA., Richbourg T; Departments of Neurology and Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, USA., Gonzalez-Hunt CP; Departments of Neurology and Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, USA., Qi R; Departments of Neurology and Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, USA., Wren P; ESCAPE Bio, Inc., South San Francisco, CA, 94080, USA., Barlow C; ESCAPE Bio, Inc., South San Francisco, CA, 94080, USA., Shanks NF; ESCAPE Bio, Inc., South San Francisco, CA, 94080, USA., Carlisle HJ; ESCAPE Bio, Inc., South San Francisco, CA, 94080, USA., Sanders LH; Departments of Neurology and Pathology, Duke University School of Medicine, Durham, NC, 27710, USA. laurie.sanders@duke.edu.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, USA. laurie.sanders@duke.edu.
Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2024 Mar 01; Vol. 10 (1), pp. 49. Date of Electronic Publication: 2024 Mar 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:2373-8057
DOI:10.1038/s41531-024-00660-y