MCL1 inhibition targets Myeloid Derived Suppressors Cells, promotes antitumor immunity and enhances the efficacy of immune checkpoint blockade.
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| Title: | MCL1 inhibition targets Myeloid Derived Suppressors Cells, promotes antitumor immunity and enhances the efficacy of immune checkpoint blockade. |
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| Authors: | Mukherjee N; University of Colorado Anschutz Medical Campus, School of Medicine, Department of Dermatology, Aurora, CO, 80045, USA., Katsnelson E; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Surgical Oncology, Aurora, CO, 80045, USA., Brunetti TM; Department of Immunology & Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; University of Colorado Cancer Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Michel K; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Medical Oncology, Aurora, CO, 80045, USA., Couts KL; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Medical Oncology, Aurora, CO, 80045, USA., Lambert KA; University of Colorado Anschutz Medical Campus, School of Medicine, Department of Dermatology, Aurora, CO, 80045, USA., Robinson WA; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Medical Oncology, Aurora, CO, 80045, USA., McCarter MD; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Surgical Oncology, Aurora, CO, 80045, USA., Norris DA; University of Colorado Anschutz Medical Campus, School of Medicine, Department of Dermatology, Aurora, CO, 80045, USA.; Department of Veterans Affairs Medical Center, Dermatology Section, Denver, CO, 80220, USA., Tobin RP; University of Colorado Anschutz Medical Campus, School of Medicine, Division of Surgical Oncology, Aurora, CO, 80045, USA. Richard.Tobin@cuanschutz.edu., Shellman YG; University of Colorado Anschutz Medical Campus, School of Medicine, Department of Dermatology, Aurora, CO, 80045, USA. Yiqun.shellman@CUAnschutz.edu.; University of Colorado Anschutz Medical Campus, Gates Center for Regenerative Medicine, Aurora, CO, 80045, USA. Yiqun.shellman@CUAnschutz.edu. |
| Source: | Cell death & disease [Cell Death Dis] 2024 Mar 08; Vol. 15 (3), pp. 198. Date of Electronic Publication: 2024 Mar 08. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-024-06524-w |
