Proteogenomic analysis of enriched HGSOC tumor epithelium identifies prognostic signatures and therapeutic vulnerabilities.
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| Title: | Proteogenomic analysis of enriched HGSOC tumor epithelium identifies prognostic signatures and therapeutic vulnerabilities. |
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| Authors: | Bateman NW; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. batemann@whirc.org.; The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc, Bethesda, MD, USA. batemann@whirc.org.; The John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University and Walter Reed National Military Medical Center, Bethesda, MD, USA. batemann@whirc.org., Abulez T; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc, Bethesda, MD, USA., Soltis AR; The American Genome Center, Collaborative Health Initiative Research Program, Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., McPherson A; Department of Computational Oncology, Memorial Sloan Kettering Cancer Center, Manhattan, NY, USA., Choi S; Department of Computational Oncology, Memorial Sloan Kettering Cancer Center, Manhattan, NY, USA., Garsed DW; Peter MacCallum Cancer Centre, Parkville, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Pandey A; Peter MacCallum Cancer Centre, Parkville, Melbourne, Victoria, Australia., Tian C; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc, Bethesda, MD, USA., Hood BL; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc, Bethesda, MD, USA., Conrads KA; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc, Bethesda, MD, USA., Teng PN; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc, Bethesda, MD, USA., Oliver J; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc, Bethesda, MD, USA., Gist G; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc, Bethesda, MD, USA., Mitchell D; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc, Bethesda, MD, USA., Litzi TJ; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc, Bethesda, MD, USA., Tarney CM; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Crothers BA; The Joint Pathology Center, Defense Health Agency, National Capital Region Medical Directorate, Silver Spring, MD, USA., Mhawech-Fauceglia P; Department of Anatomic Pathology, Division of Gynecologic Pathology, University of Southern California, Los Angeles, CA, USA., Dalgard CL; The American Genome Center, Collaborative Health Initiative Research Program, Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Wilkerson MD; The American Genome Center, Collaborative Health Initiative Research Program, Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Pierobon M; Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA., Petricoin EF; Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA., Yan C; Center for Biomedical Informatics and Information Technology, National Cancer Institute, Rockville, MD, USA., Meerzaman D; Center for Biomedical Informatics and Information Technology, National Cancer Institute, Rockville, MD, USA., Bodelon C; Division of Cancer Epidemiology and Genetics National Cancer Institute, Rockville, MD, USA., Wentzensen N; Division of Cancer Epidemiology and Genetics National Cancer Institute, Rockville, MD, USA., Lee JSH; Ellison Institute for Transformative Medicine, University of Southern California, Los Angeles, CA, USA., Huntsman DG; Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, British Columbia, Canada., Shah S; Department of Computational Oncology, Memorial Sloan Kettering Cancer Center, Manhattan, NY, USA., Shriver CD; The John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University and Walter Reed National Military Medical Center, Bethesda, MD, USA., Phippen NT; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Darcy KM; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc, Bethesda, MD, USA.; The John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University and Walter Reed National Military Medical Center, Bethesda, MD, USA., Bowtell DDL; Peter MacCallum Cancer Centre, Parkville, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Conrads TP; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. conrads@whirc.org.; The John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University and Walter Reed National Military Medical Center, Bethesda, MD, USA. conrads@whirc.org.; Women's Health Integrated Research Center, Women's Service Line, Inova Health System, Falls Church, VA, USA. conrads@whirc.org., Maxwell GL; Gynecologic Cancer Center of Excellence, Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. george.maxwell@inova.org.; The John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University and Walter Reed National Military Medical Center, Bethesda, MD, USA. george.maxwell@inova.org.; Women's Health Integrated Research Center, Women's Service Line, Inova Health System, Falls Church, VA, USA. george.maxwell@inova.org. |
| Corporate Authors: | APOLLO Research Network |
| Source: | NPJ precision oncology [NPJ Precis Oncol] 2024 Mar 13; Vol. 8 (1), pp. 68. Date of Electronic Publication: 2024 Mar 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2397-768X |
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| DOI: | 10.1038/s41698-024-00519-8 |
