Dual receptor-sites reveal the structural basis for hyperactivation of sodium channels by poison-dart toxin batrachotoxin.
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| Title: | Dual receptor-sites reveal the structural basis for hyperactivation of sodium channels by poison-dart toxin batrachotoxin. |
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| Authors: | Tonggu L; Department of Pharmacology, University of Washington, Seattle, WA, 98195, USA., Wisedchaisri G; Department of Pharmacology, University of Washington, Seattle, WA, 98195, USA., Gamal El-Din TM; Department of Pharmacology, University of Washington, Seattle, WA, 98195, USA., Lenaeus MJ; Division of General Internal Medicine, Department of Medicine, University of Washington, Seattle, WA, 98195, USA., Logan MM; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.; Vividion Therapeutics, Inc., 5820 Nancy Ridge Dr., San Diego, CA, 92121, USA., Toma T; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.; PRISM BioLab Co., Ltd., 2-26-1 Muraokahigashi, Fujisawa-shi, Kanagawa, 251-8555, Japan., Du Bois J; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA., Zheng N; Department of Pharmacology, University of Washington, Seattle, WA, 98195, USA. nzheng@uw.edu.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, 98195, USA. nzheng@uw.edu., Catterall WA; Department of Pharmacology, University of Washington, Seattle, WA, 98195, USA. wcatt@uw.edu. |
| Source: | Nature communications [Nat Commun] 2024 Mar 14; Vol. 15 (1), pp. 2306. Date of Electronic Publication: 2024 Mar 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-024-45958-w |
