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Asymmetric Synthesis of CIDD-0072424 via an Enantioselective Nitro-Mannich Reaction: A Central Nervous System Penetrant, Selective Small Molecule Inhibitor of Protein Kinase C Epsilon.

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Bibliographic Details
Title: Asymmetric Synthesis of CIDD-0072424 via an Enantioselective Nitro-Mannich Reaction: A Central Nervous System Penetrant, Selective Small Molecule Inhibitor of Protein Kinase C Epsilon.
Authors: De Kraker H; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States., Wang HL; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States., Arman HD; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States., Renteria RN; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States., Fleischer CN; College of Pharmacy, The University of Texas at Austin, Austin, Texas 78712, United States., Messing RO; College of Pharmacy, The University of Texas at Austin, Austin, Texas 78712, United States., McHardy SF; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States.
Source: The Journal of organic chemistry [J Org Chem] 2024 Apr 05; Vol. 89 (7), pp. 5134-5141. Date of Electronic Publication: 2024 Mar 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-6904
DOI:10.1021/acs.joc.3c02917