Asymmetric Synthesis of CIDD-0072424 via an Enantioselective Nitro-Mannich Reaction: A Central Nervous System Penetrant, Selective Small Molecule Inhibitor of Protein Kinase C Epsilon.
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| Title: | Asymmetric Synthesis of CIDD-0072424 via an Enantioselective Nitro-Mannich Reaction: A Central Nervous System Penetrant, Selective Small Molecule Inhibitor of Protein Kinase C Epsilon. |
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| Authors: | De Kraker H; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States., Wang HL; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States., Arman HD; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States., Renteria RN; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States., Fleischer CN; College of Pharmacy, The University of Texas at Austin, Austin, Texas 78712, United States., Messing RO; College of Pharmacy, The University of Texas at Austin, Austin, Texas 78712, United States., McHardy SF; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States. |
| Source: | The Journal of organic chemistry [J Org Chem] 2024 Apr 05; Vol. 89 (7), pp. 5134-5141. Date of Electronic Publication: 2024 Mar 15. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 38489762 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Asymmetric Synthesis of CIDD-0072424 via an Enantioselective Nitro-Mannich Reaction: A Central Nervous System Penetrant, Selective Small Molecule Inhibitor of Protein Kinase C Epsilon. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22De+Kraker+H%22">De Kraker H</searchLink>; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States.<br /><searchLink fieldCode="AU" term="%22Wang+HL%22">Wang HL</searchLink>; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States.<br /><searchLink fieldCode="AU" term="%22Arman+HD%22">Arman HD</searchLink>; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States.<br /><searchLink fieldCode="AU" term="%22Renteria+RN%22">Renteria RN</searchLink>; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States.<br /><searchLink fieldCode="AU" term="%22Fleischer+CN%22">Fleischer CN</searchLink>; College of Pharmacy, The University of Texas at Austin, Austin, Texas 78712, United States.<br /><searchLink fieldCode="AU" term="%22Messing+RO%22">Messing RO</searchLink>; College of Pharmacy, The University of Texas at Austin, Austin, Texas 78712, United States.<br /><searchLink fieldCode="AU" term="%22McHardy+SF%22">McHardy SF</searchLink>; Center for Innovative Drug Discovery, Department of Chemistry, University of Texas San Antonio, San Antonio, Texas 78254, United States. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%222985193R%22">The Journal of organic chemistry</searchLink> [J Org Chem] 2024 Apr 05; Vol. 89 (7), pp. 5134-5141. <i>Date of Electronic Publication: </i>2024 Mar 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985193R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-6904 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200223263%22">00223263 </searchLink><i>NLM ISO Abbreviation: </i>J Org Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=38489762 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acs.joc.3c02917 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 5134 Titles: – TitleFull: Asymmetric Synthesis of CIDD-0072424 via an Enantioselective Nitro-Mannich Reaction: A Central Nervous System Penetrant, Selective Small Molecule Inhibitor of Protein Kinase C Epsilon. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: De Kraker H – PersonEntity: Name: NameFull: Wang HL – PersonEntity: Name: NameFull: Arman HD – PersonEntity: Name: NameFull: Renteria RN – PersonEntity: Name: NameFull: Fleischer CN – PersonEntity: Name: NameFull: Messing RO – PersonEntity: Name: NameFull: McHardy SF IsPartOfRelationships: – BibEntity: Dates: – D: 05 M: 04 Text: 2024 Apr 05 Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 1520-6904 Numbering: – Type: volume Value: 89 – Type: issue Value: 7 Titles: – TitleFull: The Journal of organic chemistry Type: main |
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