Targeting STAT6-mediated synovial macrophage activation improves pain in experimental knee osteoarthritis.
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| Title: | Targeting STAT6-mediated synovial macrophage activation improves pain in experimental knee osteoarthritis. |
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| Authors: | Blackler G; Department of Physiology and Pharmacology, Western University, London, ON, N6A 5B5, Canada., Lai-Zhao Y; Department of Physiology and Pharmacology, Western University, London, ON, N6A 5B5, Canada.; Bone and Joint Institute, Western University, London, ON, N6A 5B5, Canada., Klapak J; Department of Physiology and Pharmacology, Western University, London, ON, N6A 5B5, Canada., Philpott HT; Department of Physiology and Pharmacology, Western University, London, ON, N6A 5B5, Canada.; Bone and Joint Institute, Western University, London, ON, N6A 5B5, Canada., Pitchers KK; Department of Physiology and Pharmacology, Western University, London, ON, N6A 5B5, Canada., Maher AR; Department of Physiology and Pharmacology, Western University, London, ON, N6A 5B5, Canada., Fiset B; Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, QC, H3A 1A3, Canada., Walsh LA; Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, QC, H3A 1A3, Canada.; Department of Human Genetics, McGill University, Montreal, QC, H3A 0C7, Canada., Gillies ER; Department of Chemistry, Western University, London, ON, N6A 5B5, Canada.; Department of Chemical and Biochemical Engineering, Western University, London, ON, N6A 5B5, Canada., Appleton CT; Department of Physiology and Pharmacology, Western University, London, ON, N6A 5B5, Canada. tom.appleton@sjhc.london.on.ca.; Bone and Joint Institute, Western University, London, ON, N6A 5B5, Canada. tom.appleton@sjhc.london.on.ca.; Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, N6A 5C1, Canada. tom.appleton@sjhc.london.on.ca. |
| Source: | Arthritis research & therapy [Arthritis Res Ther] 2024 Mar 20; Vol. 26 (1), pp. 73. Date of Electronic Publication: 2024 Mar 20. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-6362 (Electronic) Linking ISSN: 14786354 NLM ISO Abbreviation: Arthritis Res Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1478-6362 |
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| DOI: | 10.1186/s13075-024-03309-6 |