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Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles.

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Title: Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles.
Authors: Ruzanov P; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Evdokimova V; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Pachva MC; Department of Molecular Oncology, British Columbia Cancer Research Centre and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Minkovich A; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Zhang Z; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Langman S; Department of Molecular Oncology, British Columbia Cancer Research Centre and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Gassmann H; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany., Thiel U; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany., Orlic-Milacic M; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Zaidi SH; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Peltekova V; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Heisler LE; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Sharma M; Vancouver Prostate Centre, Vancouver, British Columbia, Canada., Cox ME; Vancouver Prostate Centre, Vancouver, British Columbia, Canada., McKee TD; STTARR Innovation Centre, Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.; Pathomics Inc., Toronto, Ontario, Canada., Zaidi M; Pathomics Inc., Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Lapouble E; Unité Génétique Somatique (UGS), Institut Curie, Centre Hospitalier Paris, France., McPherson JD; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Biochemistry and Molecular Medicine, University of California Davis Comprehensive Cancer Center, Sacramento, California, USA., Delattre O; Unité Génétique Somatique (UGS), Institut Curie, Centre Hospitalier Paris, France.; Diversity and Plasticity of Childhood tumors, INSERM U830, Institut Curie Research Center, PSL Research University, Paris, France., Radvanyi L; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario, Canada., Burdach SE; Department of Molecular Oncology, British Columbia Cancer Research Centre and.; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.; CCC München Comprehensive Cancer Center, DKTK German Cancer Consortium, Munich, Germany.; Institute of Pathology, Translation Pediatric Cancer Research Action, School of Medicine, Technical University of Munich, Munich, Germany., Stein LD; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Sorensen PH; Department of Molecular Oncology, British Columbia Cancer Research Centre and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Source: The Journal of clinical investigation [J Clin Invest] 2024 Mar 26; Vol. 134 (9). Date of Electronic Publication: 2024 Mar 26.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles.
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  Data: <searchLink fieldCode="AU" term="%22Ruzanov+P%22">Ruzanov P</searchLink>; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Evdokimova+V%22">Evdokimova V</searchLink>; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Pachva+MC%22">Pachva MC</searchLink>; Department of Molecular Oncology, British Columbia Cancer Research Centre and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Minkovich+A%22">Minkovich A</searchLink>; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Langman+S%22">Langman S</searchLink>; Department of Molecular Oncology, British Columbia Cancer Research Centre and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Gassmann+H%22">Gassmann H</searchLink>; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Thiel+U%22">Thiel U</searchLink>; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Orlic-Milacic+M%22">Orlic-Milacic M</searchLink>; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Zaidi+SH%22">Zaidi SH</searchLink>; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Peltekova+V%22">Peltekova V</searchLink>; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Heisler+LE%22">Heisler LE</searchLink>; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Sharma+M%22">Sharma M</searchLink>; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Cox+ME%22">Cox ME</searchLink>; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22McKee+TD%22">McKee TD</searchLink>; STTARR Innovation Centre, Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.; Pathomics Inc., Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Zaidi+M%22">Zaidi M</searchLink>; Pathomics Inc., Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Lapouble+E%22">Lapouble E</searchLink>; Unité Génétique Somatique (UGS), Institut Curie, Centre Hospitalier Paris, France.<br /><searchLink fieldCode="AU" term="%22McPherson+JD%22">McPherson JD</searchLink>; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Biochemistry and Molecular Medicine, University of California Davis Comprehensive Cancer Center, Sacramento, California, USA.<br /><searchLink fieldCode="AU" term="%22Delattre+O%22">Delattre O</searchLink>; Unité Génétique Somatique (UGS), Institut Curie, Centre Hospitalier Paris, France.; Diversity and Plasticity of Childhood tumors, INSERM U830, Institut Curie Research Center, PSL Research University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Radvanyi+L%22">Radvanyi L</searchLink>; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Burdach+SE%22">Burdach SE</searchLink>; Department of Molecular Oncology, British Columbia Cancer Research Centre and.; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.; CCC München Comprehensive Cancer Center, DKTK German Cancer Consortium, Munich, Germany.; Institute of Pathology, Translation Pediatric Cancer Research Action, School of Medicine, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Stein+LD%22">Stein LD</searchLink>; Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Sorensen+PH%22">Sorensen PH</searchLink>; Department of Molecular Oncology, British Columbia Cancer Research Centre and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2024 Mar 26; Vol. 134 (9). <i>Date of Electronic Publication: </i>2024 Mar 26.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7802877 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-8238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219738%22">00219738 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Invest <i>Subsets: </i>MEDLINE
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        Value: 10.1172/JCI169470
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        Text: English
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