Long-term safety, tolerability and efficacy of apomorphine sublingual film in patients with Parkinson's disease complicated by OFF episodes: a phase 3, open-label study.

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Title: Long-term safety, tolerability and efficacy of apomorphine sublingual film in patients with Parkinson's disease complicated by OFF episodes: a phase 3, open-label study.
Authors: Kassubek J; Department of Neurology, University Hospital Ulm, Oberer Eselsberg 45, 89081, Ulm, Germany. jan.kassubek@uni-ulm.de.; German Centre for Neurodegenerative Diseases, Ulm, Germany. jan.kassubek@uni-ulm.de., Factor SA; Jean and Paul Amos Parkinson's Disease and Movement Disorder Program, Emory University School of Medicine, Atlanta, GA, USA., Balaguer E; Hospital Universitari General de Catalunya, Barcelona, Spain., Schwarz J; Department of Geriatrics, Kreisklinik Ebersberg, Ebersberg, Germany., Chaudhuri KR; Department of Neurosciences, Institute of Psychiatry, Psychology and Neuroscience and Parkinson's Foundation Centre of Excellence, King's College Hospital, King's College London, London, UK., Isaacson SH; Parkinson's Disease and Movement Disorders Center of Boca Raton, Boca Raton, FL, USA., Wu S; Sumitomo Pharma America, Inc., Marlborough, MA, USA., Denecke Muhr C; BIAL-Portela & Ca S.A., Porto, Portugal., Kulisevsky J; Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.; Universitat Autònoma de Barcelona and CIBERNED, Madrid, Spain.
Source: Journal of neurology [J Neurol] 2024 Jun; Vol. 271 (6), pp. 3554-3570. Date of Electronic Publication: 2024 Mar 28.
Publication Type: Journal Article; Clinical Trial, Phase III; Multicenter Study
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-1459
DOI:10.1007/s00415-024-12323-2