Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes.
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| Title: | Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes. |
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| Authors: | Liu J; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Vernikovskaya D; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Bora G; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Carlo A; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Burchett W; Global Biometrics and Data Management, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Jordan S; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Tang LWT; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Yang J; Medicinal Chemistry, Pfizer Worldwide Research and Development, Cambridge, Massachusetts, USA., Che Y; Discovery Sciences, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Chang G; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Troutman MD; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut, USA., Di L; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut, USA. li.di@recursionpharma.com.; Recursion Pharmaceuticals, Salt Lake City, UT, USA. li.di@recursionpharma.com. |
| Source: | The AAPS journal [AAPS J] 2024 Mar 28; Vol. 26 (3), pp. 36. Date of Electronic Publication: 2024 Mar 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1550-7416 |
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| DOI: | 10.1208/s12248-024-00908-8 |
