Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer's disease reveals distinct sequential responses to Aβ and tau.

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Title: Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer's disease reveals distinct sequential responses to Aβ and tau.
Authors: Wachter A; AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany., Woodbury ME; AbbVie Inc., Cambridge, MA, USA. maya.woodbury@abbvie.com., Lombardo S; AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany., Abdourahman A; AbbVie Inc., Cambridge, MA, USA., Wuest C; AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany., McGlame E; AbbVie Inc., Cambridge, MA, USA., Pastika T; AbbVie Inc., Cambridge, MA, USA., Tamm J; AbbVie Inc., Cambridge, MA, USA., Romanul N; AbbVie Inc., Cambridge, MA, USA., Yanamandra K; AbbVie Inc., Cambridge, MA, USA., Bennett R; Massachusetts General Hospital, Boston, USA.; Harvard Medical School, Boston, USA., Lin G; AbbVie Pte Ltd, Singapore, Singapore., Kwon T; AbbVie Inc., Cambridge, MA, USA., Liao F; AbbVie Inc., Cambridge, MA, USA., Klein C; AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany., Grinberg Y; AbbVie Inc., Cambridge, MA, USA., Jaisa-Aad M; Massachusetts General Hospital, Boston, USA.; Harvard Medical School, Boston, USA., Li H; Massachusetts General Hospital, Boston, USA.; Harvard Medical School, Boston, USA., Frosch MP; Massachusetts General Hospital, Boston, USA.; Harvard Medical School, Boston, USA.; Massachusetts Alzheimer's Disease Research Center, Charlestown, USA., Kummer MP; AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany., Das S; Massachusetts General Hospital, Boston, USA.; Harvard Medical School, Boston, USA.; Massachusetts Alzheimer's Disease Research Center, Charlestown, USA., Dellovade T; AbbVie Inc., Cambridge, MA, USA., Karran EH; AbbVie Inc., Cambridge, MA, USA., Langlois X; AbbVie Inc., Cambridge, MA, USA., Ried JS; AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany., Serrano-Pozo A; Massachusetts General Hospital, Boston, USA.; Harvard Medical School, Boston, USA.; Massachusetts Alzheimer's Disease Research Center, Charlestown, USA., Talanian RV; AbbVie Inc., Cambridge, MA, USA., Biber K; AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany., Hyman BT; Massachusetts General Hospital, Boston, USA.; Harvard Medical School, Boston, USA.; Massachusetts Alzheimer's Disease Research Center, Charlestown, USA.
Source: Acta neuropathologica [Acta Neuropathol] 2024 Apr 01; Vol. 147 (1), pp. 65. Date of Electronic Publication: 2024 Apr 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0533
DOI:10.1007/s00401-024-02704-2