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Development of a pan-tau multivalent nanobody that binds tau aggregation motifs and recognizes pathological tau aggregates.

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Title: Development of a pan-tau multivalent nanobody that binds tau aggregation motifs and recognizes pathological tau aggregates.
Authors: McArthur N; School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA., Kang B; School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA., Rivera Moctezuma FG; George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA., Shaikh AT; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA., Loeffler K; School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA., Bhatt NN; Mitchell Center for Neurodegenerative Disease, University of Texas Medical Branch, Galveston, Texas, USA.; Department of Neurology, University of Texas Medical Branch, Galveston, Texas, USA., Kidd M; Mitchell Center for Neurodegenerative Disease, University of Texas Medical Branch, Galveston, Texas, USA.; Department of Neurology, University of Texas Medical Branch, Galveston, Texas, USA., Zupancic JM; Department of Chemical Engineering, University of Michigan, North Campus Research Complex, Ann Arbor, Michigan, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, USA., Desai AA; Department of Chemical Engineering, University of Michigan, North Campus Research Complex, Ann Arbor, Michigan, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, USA., Djeddar N; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA., Bryksin A; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA., Tessier PM; Department of Chemical Engineering, University of Michigan, North Campus Research Complex, Ann Arbor, Michigan, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, USA.; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, USA.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA., Kayed R; Mitchell Center for Neurodegenerative Disease, University of Texas Medical Branch, Galveston, Texas, USA.; Department of Neurology, University of Texas Medical Branch, Galveston, Texas, USA., Wood LB; George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA., Kane RS; School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA.
Source: Biotechnology progress [Biotechnol Prog] 2024 Sep-Oct; Vol. 40 (5), pp. e3463. Date of Electronic Publication: 2024 Apr 03.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8506292 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6033 (Electronic) Linking ISSN: 15206033 NLM ISO Abbreviation: Biotechnol Prog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Development of a pan-tau multivalent nanobody that binds tau aggregation motifs and recognizes pathological tau aggregates.
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  Data: <searchLink fieldCode="AU" term="%22McArthur+N%22">McArthur N</searchLink>; School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Kang+B%22">Kang B</searchLink>; School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Rivera+Moctezuma+FG%22">Rivera Moctezuma FG</searchLink>; George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Shaikh+AT%22">Shaikh AT</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Loeffler+K%22">Loeffler K</searchLink>; School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Bhatt+NN%22">Bhatt NN</searchLink>; Mitchell Center for Neurodegenerative Disease, University of Texas Medical Branch, Galveston, Texas, USA.; Department of Neurology, University of Texas Medical Branch, Galveston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Kidd+M%22">Kidd M</searchLink>; Mitchell Center for Neurodegenerative Disease, University of Texas Medical Branch, Galveston, Texas, USA.; Department of Neurology, University of Texas Medical Branch, Galveston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Zupancic+JM%22">Zupancic JM</searchLink>; Department of Chemical Engineering, University of Michigan, North Campus Research Complex, Ann Arbor, Michigan, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Desai+AA%22">Desai AA</searchLink>; Department of Chemical Engineering, University of Michigan, North Campus Research Complex, Ann Arbor, Michigan, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Djeddar+N%22">Djeddar N</searchLink>; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Bryksin+A%22">Bryksin A</searchLink>; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Tessier+PM%22">Tessier PM</searchLink>; Department of Chemical Engineering, University of Michigan, North Campus Research Complex, Ann Arbor, Michigan, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, USA.; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, USA.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Kayed+R%22">Kayed R</searchLink>; Mitchell Center for Neurodegenerative Disease, University of Texas Medical Branch, Galveston, Texas, USA.; Department of Neurology, University of Texas Medical Branch, Galveston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Wood+LB%22">Wood LB</searchLink>; George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Kane+RS%22">Kane RS</searchLink>; School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, USA.
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