Feasibility, safety, and impact of the RTS,S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi.

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Title: Feasibility, safety, and impact of the RTS,S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi.
Authors: Asante KP; Kintampo Health Research Centre, Research and Development Division, Ghana Health Service, Kintampo North Municipality, Ghana; London School of Hygiene & Tropical Medicine, London, UK. Electronic address: kwakupoku.asante@kintampo-hrc.org., Mathanga DP; School of Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi; Malaria Alert Centre, Kamuzu University of Health Sciences, Blantyre, Malawi., Milligan P; London School of Hygiene & Tropical Medicine, London, UK. Electronic address: paul.milligan@lshtm.ac.uk., Akech S; Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Nairobi, Kenya., Oduro A; Navrongo Health Research Centre, Research and Development Division, Ghana Health Service, Accra, Ghana., Mwapasa V; School of Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi., Moore KA; London School of Hygiene & Tropical Medicine, London, UK; Murdoch Children's Research Institute, Infection and Immunity, New Vaccines, Parkville, VIC, Australia., Kwambai TK; Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Kisumu, Kenya., Hamel MJ; Department of Immunizations, Vaccines, and Biologicals, WHO, Geneva, Switzerland., Gyan T; Kintampo Health Research Centre, Research and Development Division, Ghana Health Service, Kintampo North Municipality, Ghana., Westercamp N; Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA., Kapito-Tembo A; School of Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi., Njuguna P; Global Malaria Programme, WHO, Geneva, Switzerland., Ansong D; Agogo Malaria Research Centre, Agogo, Ghana; Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Kariuki S; Centre for Global Health Research, KEMRI, Kisumu, Kenya., Mvalo T; University of North Carolina Project-Malawi, Lilongwe, Malawi., Snell P; London School of Hygiene & Tropical Medicine, London, UK., Schellenberg D; Global Malaria Programme, WHO, Geneva, Switzerland., Welega P; Navrongo Health Research Centre, Research and Development Division, Ghana Health Service, Accra, Ghana., Otieno L; KEMRI-US Army Medical Research Directorate-Africa, Kisumu, Kenya., Chimala A; Malaria Alert Centre, Kamuzu University of Health Sciences, Blantyre, Malawi., Afari EA; School of Public Health, University of Ghana, Accra, Ghana., Bejon P; Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Nairobi, Kenya; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Maleta K; School of Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi., Agbenyega T; Agogo Malaria Research Centre, Agogo, Ghana; Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Snow RW; Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Nairobi, Kenya; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Zulu M; University of North Carolina Project-Malawi, Lilongwe, Malawi., Chinkhumba J; School of Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi., Samuels AM; Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Kisumu, Kenya; Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: amsamuels@cdc.gov.
Corporate Authors: Malaria Vaccine Programme Evaluation Partners
Source: Lancet (London, England) [Lancet] 2024 Apr 27; Vol. 403 (10437), pp. 1660-1670. Date of Electronic Publication: 2024 Apr 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1474-547X
DOI:10.1016/S0140-6736(24)00004-7