Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells.

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Title: Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells.
Authors: Ghiasi SM; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.; Development and Aging Program, and Human Genetics Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, United States., Marchetti P; Department of Clinical and Experimental Medicine, Islet Cell Laboratory, University of Pisa, Pisa, Italy., Piemonti L; Diabetes Research Institute, Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Milano, Italy., Nielsen JH; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Porse BT; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark.; The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.; Danish Stem Cell Center (DanStem) Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark., Mandrup-Poulsen T; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Rutter GA; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom.; Centre Hospitalier de l'Université de Montréal (CHUM) Research Centre (CRCHUM) and Faculty of Medicine, University of Montreal, Montreal, QC, Canada.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2024 Mar 22; Vol. 15, pp. 1359147. Date of Electronic Publication: 2024 Mar 22 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1664-2392
DOI:10.3389/fendo.2024.1359147