Mitomycin C and its analog trigger cytotoxicity in MCF-7 and K562 cancer cells through the regulation of RAS and MAPK/ERK pathways.

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Title: Mitomycin C and its analog trigger cytotoxicity in MCF-7 and K562 cancer cells through the regulation of RAS and MAPK/ERK pathways.
Authors: Zacarias O; Department of Sciences, John Jay College of Criminal Justice, The City University of New York, New York, NY, 10019, USA., Clement CC; Radiation Oncology Department, Weill Cornell Medicine, New York, New York, 10065, USA. Electronic address: ccc4002@med.cornell.edu., Cheng SY; Department of Sciences, John Jay College of Criminal Justice, The City University of New York, New York, NY, 10019, USA; Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY, 10016, USA. Electronic address: shcheng@jjay.cuny.edu., Rosas M; Department of Sciences, John Jay College of Criminal Justice, The City University of New York, New York, NY, 10019, USA., Gonzalez C; Department of Sciences, John Jay College of Criminal Justice, The City University of New York, New York, NY, 10019, USA., Peter M; IRCM, University Montpellier, ICM, INSERM, CNRS, Campus Val d'Aurelle, 208 avenue des apothicaires, 34298, Montpellier, Cédex 5, France., Coopman P; IRCM, University Montpellier, ICM, INSERM, CNRS, Campus Val d'Aurelle, 208 avenue des apothicaires, 34298, Montpellier, Cédex 5, France., Champeil E; Department of Sciences, John Jay College of Criminal Justice, The City University of New York, New York, NY, 10019, USA; Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, NY, 10016, USA. Electronic address: echampeil@jjay.cuny.edu.
Source: Chemico-biological interactions [Chem Biol Interact] 2024 May 25; Vol. 395, pp. 111007. Date of Electronic Publication: 2024 Apr 18.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-7786
DOI:10.1016/j.cbi.2024.111007