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Live-cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a.

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Title: Live-cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a.
Authors: Olivi L; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands., Bagchus C; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands., Pool V; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands., Bekkering E; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands., Speckner K; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands., Offerhaus H; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, The Netherlands., Wu WY; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands., Depken M; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, The Netherlands., Martens KJA; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands., Staals RHJ; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands., Hohlbein J; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands.; Microspectroscopy Research Facility, Wageningen University & Research, Wageningen, The Netherlands.
Source: Nucleic acids research [Nucleic Acids Res] 2024 May 22; Vol. 52 (9), pp. 5241-5256.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Live-cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a.
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  Data: <searchLink fieldCode="AU" term="%22Olivi+L%22">Olivi L</searchLink>; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bagchus+C%22">Bagchus C</searchLink>; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pool+V%22">Pool V</searchLink>; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bekkering+E%22">Bekkering E</searchLink>; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Speckner+K%22">Speckner K</searchLink>; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Offerhaus+H%22">Offerhaus H</searchLink>; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wu+WY%22">Wu WY</searchLink>; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Depken+M%22">Depken M</searchLink>; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Martens+KJA%22">Martens KJA</searchLink>; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Staals+RHJ%22">Staals RHJ</searchLink>; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hohlbein+J%22">Hohlbein J</searchLink>; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands.; Microspectroscopy Research Facility, Wageningen University & Research, Wageningen, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%220411011%22">Nucleic acids research</searchLink> [Nucleic Acids Res] 2024 May 22; Vol. 52 (9), pp. 5241-5256.
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              Text: 2024 May 22
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