Live-cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a.
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| Title: | Live-cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a. |
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| Authors: | Olivi L; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands., Bagchus C; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands., Pool V; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands., Bekkering E; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands., Speckner K; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands., Offerhaus H; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, The Netherlands., Wu WY; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands., Depken M; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, The Netherlands., Martens KJA; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands., Staals RHJ; Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands., Hohlbein J; Laboratory of Biophysics, Wageningen University & Research, Wageningen, The Netherlands.; Microspectroscopy Research Facility, Wageningen University & Research, Wageningen, The Netherlands. |
| Source: | Nucleic acids research [Nucleic Acids Res] 2024 May 22; Vol. 52 (9), pp. 5241-5256. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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