Covalent Polymer-RNA Conjugates for Potent Activation of the RIG-I Pathway.

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Title: Covalent Polymer-RNA Conjugates for Potent Activation of the RIG-I Pathway.
Authors: Palmer CR; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, 37235, USA., Pastora LE; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, 37235, USA., Kimmel BR; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, 37235, USA., Pagendarm HM; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, 37235, USA., Kwiatkowski AJ; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, 37235, USA., Stone PT; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, 37235, USA., Arora K; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, 37235, USA., Francini N; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, 37235, USA., Fedorova O; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, 06511, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, 20815, USA., Pyle AM; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, 06511, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, 20815, USA.; Department of Chemistry, Yale University, New Haven, CT, 06511, USA., Wilson JT; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, 37235, USA.; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, 37235, USA.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Source: Advanced healthcare materials [Adv Healthc Mater] 2025 Feb; Vol. 14 (5), pp. e2303815. Date of Electronic Publication: 2024 May 03.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101581613 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2192-2659 (Electronic) Linking ISSN: 21922640 NLM ISO Abbreviation: Adv Healthc Mater Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2192-2659
DOI:10.1002/adhm.202303815