Unconventional activation of PRKDC by TNF-α: deciphering its crucial role in Th1-mediated inflammation beyond DNA repair as part of the DNA-PK complex.

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Title: Unconventional activation of PRKDC by TNF-α: deciphering its crucial role in Th1-mediated inflammation beyond DNA repair as part of the DNA-PK complex.
Authors: Ghonim MA; The Stanley S. Scott Cancer Center, LSU Health Sciences Center-New Orleans, 1700 Tulane Ave, New Orleans, LA, 70112, USA.; Department of Microbiology and Immunology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt., Ju J; The Stanley S. Scott Cancer Center, LSU Health Sciences Center-New Orleans, 1700 Tulane Ave, New Orleans, LA, 70112, USA., Pyakurel K; The Stanley S. Scott Cancer Center, LSU Health Sciences Center-New Orleans, 1700 Tulane Ave, New Orleans, LA, 70112, USA., Ibba SV; The Stanley S. Scott Cancer Center, LSU Health Sciences Center-New Orleans, 1700 Tulane Ave, New Orleans, LA, 70112, USA., Abouzeid MM; The Stanley S. Scott Cancer Center, LSU Health Sciences Center-New Orleans, 1700 Tulane Ave, New Orleans, LA, 70112, USA., Rady HF; The Stanley S. Scott Cancer Center, LSU Health Sciences Center-New Orleans, 1700 Tulane Ave, New Orleans, LA, 70112, USA.; Department of Microbiology and Immunology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt., Matsuyama S; Department of Ophthalmology and Visual Science; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA., Del Valle L; The Stanley S. Scott Cancer Center, LSU Health Sciences Center-New Orleans, 1700 Tulane Ave, New Orleans, LA, 70112, USA., Boulares AH; The Stanley S. Scott Cancer Center, LSU Health Sciences Center-New Orleans, 1700 Tulane Ave, New Orleans, LA, 70112, USA. hboulr@lsuhsc.edu.
Source: Journal of inflammation (London, England) [J Inflamm (Lond)] 2024 Apr 30; Vol. 21 (1), pp. 14. Date of Electronic Publication: 2024 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101232234 Publication Model: Electronic Cited Medium: Print ISSN: 1476-9255 (Print) Linking ISSN: 14769255 NLM ISO Abbreviation: J Inflamm (Lond) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1476-9255
DOI:10.1186/s12950-024-00386-x