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Loss of tumor-derived SMAD4 enhances primary tumor growth but not metastasis following BMP4 signalling.

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Title: Loss of tumor-derived SMAD4 enhances primary tumor growth but not metastasis following BMP4 signalling.
Authors: Chi LH; Olivia Newton-John Cancer Research Institute, 145 Studley Road, Heidelberg, VIC, 3084, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, VIC, Australia., Redfern AD; Harry Perkins Institute of Medical Research, University of Western Australia, Perth, WA, Australia., Roslan S; Department of Surgery, St. Vincent's Hospital, Fitzroy, VIC, Australia., Street IP; Children's Cancer Institute, University of New South Wales, New South Wales, Australia., Burrows AD; Olivia Newton-John Cancer Research Institute, 145 Studley Road, Heidelberg, VIC, 3084, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, VIC, Australia., Anderson RL; Olivia Newton-John Cancer Research Institute, 145 Studley Road, Heidelberg, VIC, 3084, Australia. robin.anderson@onjcri.org.au.; School of Cancer Medicine, La Trobe University, Bundoora, VIC, Australia. robin.anderson@onjcri.org.au.; Department of Clinical Pathology, The University of Melbourne, Parkville, VIC, Australia. robin.anderson@onjcri.org.au.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia. robin.anderson@onjcri.org.au.
Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Apr 30; Vol. 22 (1), pp. 248. Date of Electronic Publication: 2024 Apr 30.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1478-811X
DOI:10.1186/s12964-024-01559-0