RNA aggregates harness the danger response for potent cancer immunotherapy.

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Title: RNA aggregates harness the danger response for potent cancer immunotherapy.
Authors: Mendez-Gomez HR; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., DeVries A; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Castillo P; University of Florida, Department of Pediatrics, Division of Hematology-Oncology, Gainesville, FL 32610, USA., von Roemeling C; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Qdaisat S; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA; University of Florida Genetics Institute, Gainesville, FL 32610, USA., Stover BD; University of Florida, Department of Pediatrics, Division of Hematology-Oncology, Gainesville, FL 32610, USA., Xie C; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Weidert F; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Zhao C; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Moor R; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Liu R; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Soni D; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Ogando-Rivas E; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Chardon-Robles J; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., McGuiness J; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Zhang D; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Chung MC; University of Texas at Austin, College of Pharmacy, Division of Chemical Biology and Medicinal Chemistry, Austin TX 78712., Marconi C; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Michel S; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Barpujari A; University of Florida, Department of Pediatrics, Division of Hematology-Oncology, Gainesville, FL 32610, USA., Jobin GW; University of Florida, Department of Pediatrics, Division of Hematology-Oncology, Gainesville, FL 32610, USA., Thomas N; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Ma X; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA; University of Florida, Department of Pediatrics, Division of Hematology-Oncology, Gainesville, FL 32610, USA., Campaneria Y; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Grippin A; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Karachi A; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Li D; University of Florida, Division of Quantitative Sciences, UF Health Cancer Center, Gainesville, FL 32610, USA., Sahay B; University of Florida, College of Veterinary Medicine, Gainesville, FL 32610, USA., Elliott L; University of Florida, Department of Medicine, Division of Hematology-Oncology, Gainesville, FL 32610, USA., Foster TP; University of Florida, Department of Pediatrics, Division of Hematology-Oncology, Gainesville, FL 32610, USA., Coleman KE; University of Florida, Department of Pediatrics, Division of Hematology-Oncology, Gainesville, FL 32610, USA., Milner RJ; University of Florida, College of Veterinary Medicine, Gainesville, FL 32610, USA., Sawyer WG; H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Ligon JA; University of Florida, Department of Pediatrics, Division of Hematology-Oncology, Gainesville, FL 32610, USA., Simon E; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Cleaver B; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Wynne K; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Hodik M; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Molinaro AM; University of California, San Francisco, Department of Neurological Surgery, San Francisco, CA 94158, USA., Guan J; University of Texas at Austin, College of Pharmacy, Division of Chemical Biology and Medicinal Chemistry, Austin TX 78712., Kellish P; University of Florida Interdisciplinary Center for Biotechnology Research, Gainesville, FL 32610, USA., Doty A; University of Florida Interdisciplinary Center for Biotechnology Research, Gainesville, FL 32610, USA., Lee JH; University of Florida, Department of Biostatistics, Gainesville, FL 32610, USA., Massini T; University of Florida, Department of Radiology, Gainesville, FL 32610, USA., Kresak JL; University of Florida, Department of Pathology, Gainesville, FL 32610, USA., Huang J; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Hwang EI; Children's National Hospital, Center for Cancer and Blood Disorders, Washington, DC 20010, USA., Kline C; University of Pennsylvania Perelman School of Medicine, Children's Hospital of Philadelphia, Department of Pediatrics, Division of Oncology, Philadelphia, PA 19104, USA., Carrera-Justiz S; University of Florida, College of Veterinary Medicine, Gainesville, FL 32610, USA., Rahman M; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Gatica S; University of Florida, Department of Anesthesiology, Gainesville, FL 32610, USA., Mueller S; University of California, San Francisco, Department of Neurology, Neurological Surgery, and Pediatrics, San Francisco, CA 94158, USA., Prados M; University of California, San Francisco, Department of Neurological Surgery, San Francisco, CA 94158, USA., Ghiaseddin AP; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Silver NL; Cleveland Clinic, Center of Immunotherapy and Precision Immuno-Oncology/Head and Neck Institute, Cleveland, OH 44106, USA., Mitchell DA; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA., Sayour EJ; University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA; University of Florida, Department of Pediatrics, Division of Hematology-Oncology, Gainesville, FL 32610, USA. Electronic address: elias.sayour@neurosurgery.ufl.edu.
Source: Cell [Cell] 2024 May 09; Vol. 187 (10), pp. 2521-2535.e21. Date of Electronic Publication: 2024 May 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
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  Data: RNA aggregates harness the danger response for potent cancer immunotherapy.
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  Data: <searchLink fieldCode="JN" term="%220413066%22">Cell</searchLink> [Cell] 2024 May 09; Vol. 187 (10), pp. 2521-2535.e21. <i>Date of Electronic Publication: </i>2024 May 01.
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      – PersonEntity:
          Name:
            NameFull: Wynne K
      – PersonEntity:
          Name:
            NameFull: Hodik M
      – PersonEntity:
          Name:
            NameFull: Molinaro AM
      – PersonEntity:
          Name:
            NameFull: Guan J
      – PersonEntity:
          Name:
            NameFull: Kellish P
      – PersonEntity:
          Name:
            NameFull: Doty A
      – PersonEntity:
          Name:
            NameFull: Lee JH
      – PersonEntity:
          Name:
            NameFull: Massini T
      – PersonEntity:
          Name:
            NameFull: Kresak JL
      – PersonEntity:
          Name:
            NameFull: Huang J
      – PersonEntity:
          Name:
            NameFull: Hwang EI
      – PersonEntity:
          Name:
            NameFull: Kline C
      – PersonEntity:
          Name:
            NameFull: Carrera-Justiz S
      – PersonEntity:
          Name:
            NameFull: Rahman M
      – PersonEntity:
          Name:
            NameFull: Gatica S
      – PersonEntity:
          Name:
            NameFull: Mueller S
      – PersonEntity:
          Name:
            NameFull: Prados M
      – PersonEntity:
          Name:
            NameFull: Ghiaseddin AP
      – PersonEntity:
          Name:
            NameFull: Silver NL
      – PersonEntity:
          Name:
            NameFull: Mitchell DA
      – PersonEntity:
          Name:
            NameFull: Sayour EJ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 09
              M: 05
              Text: 2024 May 09
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 1097-4172
          Numbering:
            – Type: volume
              Value: 187
            – Type: issue
              Value: 10
          Titles:
            – TitleFull: Cell
              Type: main
ResultId 1