Safety and immunogenicity of Ad26.COV2.S in adults: A randomised, double-blind, placebo-controlled Phase 2a dose-finding study.

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Title: Safety and immunogenicity of Ad26.COV2.S in adults: A randomised, double-blind, placebo-controlled Phase 2a dose-finding study.
Authors: Cárdenas V; Janssen Research & Development LLC, Spring House, PA, United States. Electronic address: cardenasv@yahoo.com., Le Gars M; Janssen Vaccines & Prevention, Leiden, the Netherlands. Electronic address: Mathieu.legars1@gmail.com., Truyers C; Janssen Research & Development, Beerse Belgium. Electronic address: ctruyers@its.jnj.com., Ruiz-Guiñazú J; Janssen Research & Development, Beerse Belgium. Electronic address: JRuizGui@its.jnj.com., Struyf F; Janssen Research & Development, Beerse Belgium. Electronic address: fstruyf@gmail.com., Colfer A; Janssen Research & Development LLC, Spring House, PA, United States. Electronic address: acolfer@its.jnj.com., Bonten M; Julius Center for Health Services and Primary Care, UMC Utrecht, Utrecht University and European Clinical Alliance on Infectious Diseases, Utrecht, the Netherlands. Electronic address: m.j.m.bonten@umcutrecht.nl., Borobia A; Clinical Pharmacology Department, La Paz University Hospital. School of Medicine, Universidad Autónoma de Madrid, IdiPAZ. CIBERINFECT, Spain. Electronic address: alberto.borobia@salud.madrid.org., Reisinger EC; Rostock University Medical Center, Dept. of Infectious Diseases and Tropical Medicine, Rostock, Germany. Electronic address: emil.reisinger@uni-rostock.de., Kamerling IMC; Centre for Human Drug Research, Zernikedreef 8, 2333 CL Leiden, the Netherlands. Electronic address: idvisser@chdr.nl., Douoguih M; Janssen Vaccines & Prevention, Leiden, the Netherlands. Electronic address: macaya.douoguih@merck.com., Sadoff J; Janssen Vaccines & Prevention, Leiden, the Netherlands. Electronic address: Jerry@Centivax.com.
Source: Vaccine [Vaccine] 2024 Jun 11; Vol. 42 (16), pp. 3536-3546. Date of Electronic Publication: 2024 May 04.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8406899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2518 (Electronic) Linking ISSN: 0264410X NLM ISO Abbreviation: Vaccine Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-2518
DOI:10.1016/j.vaccine.2024.04.059