A comparison of the activity, lysosomal stability, and efficacy of legumain-cleavable and cathepsin-cleavable ADC linkers.
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| Title: | A comparison of the activity, lysosomal stability, and efficacy of legumain-cleavable and cathepsin-cleavable ADC linkers. |
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| Authors: | Gray ME; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Zielinski KM; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Xu F; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Elder KK; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., McKay SJ; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Ojo VT; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Benjamin SR; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Yaseen AA; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Brooks TA; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Tumey LN; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA. |
| Source: | Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2024 Aug; Vol. 54 (8), pp. 458-468. Date of Electronic Publication: 2024 Sep 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1366-5928 |
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| DOI: | 10.1080/00498254.2024.2352051 |
