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A comparison of the activity, lysosomal stability, and efficacy of legumain-cleavable and cathepsin-cleavable ADC linkers.

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Title: A comparison of the activity, lysosomal stability, and efficacy of legumain-cleavable and cathepsin-cleavable ADC linkers.
Authors: Gray ME; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Zielinski KM; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Xu F; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Elder KK; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., McKay SJ; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Ojo VT; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Benjamin SR; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Yaseen AA; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Brooks TA; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA., Tumey LN; Binghamton University, School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA.
Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2024 Aug; Vol. 54 (8), pp. 458-468. Date of Electronic Publication: 2024 Sep 27.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE
Database: MEDLINE Ultimate
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        Value: 10.1080/00498254.2024.2352051
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              Text: 2024 Aug
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