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Identification and characterization of a nonbiological small-molecular mimic of a Zika virus conformational neutralizing epitope.

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Title: Identification and characterization of a nonbiological small-molecular mimic of a Zika virus conformational neutralizing epitope.
Authors: Castanha PMS; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261., McEnaney PJ; Department of Chemistry, The Herbert Wertheim University of Florida Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458., Park Y; Department of Biostatistics, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261., Bouwer A; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15219., Chaves EJF; Department of Virology, Aggeu Magalhaes Institute, Oswaldo Cruz Foundation, Cidade Universitearia, Recife, Pernambuco 50740-465, Brazil., Lins RD; Department of Virology, Aggeu Magalhaes Institute, Oswaldo Cruz Foundation, Cidade Universitearia, Recife, Pernambuco 50740-465, Brazil., Paciaroni NG; Deluge Biotechnologies, Jupiter, FL 33458., Dickson P; Department of Chemistry, The Herbert Wertheim University of Florida Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458., Carlson G; Deluge Biotechnologies, Jupiter, FL 33458., Cordeiro MT; Department of Virology, Aggeu Magalhaes Institute, Oswaldo Cruz Foundation, Cidade Universitearia, Recife, Pernambuco 50740-465, Brazil., Magalhaes T; Department of Entomology, Texas A&M University, College Station, TX 77843.; Department of Preventive and Social Medicine, School of Medicine, Universidade Federal da Bahia, Bahia 40026-010, Brazil., Craigo J; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15219., Marques ETA; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261.; Department of Virology, Aggeu Magalhaes Institute, Oswaldo Cruz Foundation, Cidade Universitearia, Recife, Pernambuco 50740-465, Brazil., Kodadek T; Department of Chemistry, The Herbert Wertheim University of Florida Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458., Burke DS; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 May 21; Vol. 121 (21), pp. e2312755121. Date of Electronic Publication: 2024 May 14.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Castanha+PMS%22">Castanha PMS</searchLink>; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261.<br /><searchLink fieldCode="AU" term="%22McEnaney+PJ%22">McEnaney PJ</searchLink>; Department of Chemistry, The Herbert Wertheim University of Florida Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458.<br /><searchLink fieldCode="AU" term="%22Park+Y%22">Park Y</searchLink>; Department of Biostatistics, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261.<br /><searchLink fieldCode="AU" term="%22Bouwer+A%22">Bouwer A</searchLink>; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15219.<br /><searchLink fieldCode="AU" term="%22Chaves+EJF%22">Chaves EJF</searchLink>; Department of Virology, Aggeu Magalhaes Institute, Oswaldo Cruz Foundation, Cidade Universitearia, Recife, Pernambuco 50740-465, Brazil.<br /><searchLink fieldCode="AU" term="%22Lins+RD%22">Lins RD</searchLink>; Department of Virology, Aggeu Magalhaes Institute, Oswaldo Cruz Foundation, Cidade Universitearia, Recife, Pernambuco 50740-465, Brazil.<br /><searchLink fieldCode="AU" term="%22Paciaroni+NG%22">Paciaroni NG</searchLink>; Deluge Biotechnologies, Jupiter, FL 33458.<br /><searchLink fieldCode="AU" term="%22Dickson+P%22">Dickson P</searchLink>; Department of Chemistry, The Herbert Wertheim University of Florida Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458.<br /><searchLink fieldCode="AU" term="%22Carlson+G%22">Carlson G</searchLink>; Deluge Biotechnologies, Jupiter, FL 33458.<br /><searchLink fieldCode="AU" term="%22Cordeiro+MT%22">Cordeiro MT</searchLink>; Department of Virology, Aggeu Magalhaes Institute, Oswaldo Cruz Foundation, Cidade Universitearia, Recife, Pernambuco 50740-465, Brazil.<br /><searchLink fieldCode="AU" term="%22Magalhaes+T%22">Magalhaes T</searchLink>; Department of Entomology, Texas A&M University, College Station, TX 77843.; Department of Preventive and Social Medicine, School of Medicine, Universidade Federal da Bahia, Bahia 40026-010, Brazil.<br /><searchLink fieldCode="AU" term="%22Craigo+J%22">Craigo J</searchLink>; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15219.<br /><searchLink fieldCode="AU" term="%22Marques+ETA%22">Marques ETA</searchLink>; Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261.; Department of Virology, Aggeu Magalhaes Institute, Oswaldo Cruz Foundation, Cidade Universitearia, Recife, Pernambuco 50740-465, Brazil.<br /><searchLink fieldCode="AU" term="%22Kodadek+T%22">Kodadek T</searchLink>; Department of Chemistry, The Herbert Wertheim University of Florida Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458.<br /><searchLink fieldCode="AU" term="%22Burke+DS%22">Burke DS</searchLink>; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261.
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