Production of deoxycholic acid by low-abundant microbial species is associated with impaired glucose metabolism.

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Title: Production of deoxycholic acid by low-abundant microbial species is associated with impaired glucose metabolism.
Authors: Wahlström A; Wallenberg Laboratory and Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Brumbaugh A; Department of Bioengineering, Stanford University, Stanford, CA, USA.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford University, Stanford, CA, USA.; ChEM-H Institute, Stanford University, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Sjöland W; Wallenberg Laboratory and Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Olsson L; Wallenberg Laboratory and Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Wu H; State Key Laboratory of Genetic Engineering, Human Phenome Institute, Fudan Microbiome Center, and Department of Bariatric and Metabolic Surgery, Huashan Hospital, Fudan University, Shanghai, China., Henricsson M; Wallenberg Laboratory and Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Lundqvist A; Wallenberg Laboratory and Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Makki K; Wallenberg Laboratory and Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Hazen SL; Department of Cardiovascular & Metabolic Sciences, Lerner Research Institute, Cleveland, OH, USA.; Center for Microbiome and Human Health, Cleveland Clinic, Cleveland, OH, USA.; Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH, USA., Bergström G; Wallenberg Laboratory and Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Region Västra Götaland, Sahlgrenska University Hospital, Department of Clinical Physiology, Gothenburg, Sweden., Marschall HU; Wallenberg Laboratory and Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Fischbach MA; Department of Bioengineering, Stanford University, Stanford, CA, USA. fischbach@fischbachgroup.org.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford University, Stanford, CA, USA. fischbach@fischbachgroup.org.; ChEM-H Institute, Stanford University, Stanford, CA, USA. fischbach@fischbachgroup.org.; Chan Zuckerberg Biohub, San Francisco, CA, USA. fischbach@fischbachgroup.org., Bäckhed F; Wallenberg Laboratory and Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Fredrik.Backhed@wlab.gu.se.; Region Västra Götaland, Sahlgrenska University Hospital, Department of Clinical Physiology, Gothenburg, Sweden. Fredrik.Backhed@wlab.gu.se.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. Fredrik.Backhed@wlab.gu.se.
Source: Nature communications [Nat Commun] 2024 May 20; Vol. 15 (1), pp. 4276. Date of Electronic Publication: 2024 May 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-024-48543-3