Cardiac index-guided therapy to maintain optimised postinduction cardiac index in high-risk patients having major open abdominal surgery: the multicentre randomised iPEGASUS trial.

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Title: Cardiac index-guided therapy to maintain optimised postinduction cardiac index in high-risk patients having major open abdominal surgery: the multicentre randomised iPEGASUS trial.
Authors: Funcke S; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Schmidt G; Department of Anesthesiology, Operative Intensive Care and Pain Therapy, Justus-Liebig-University Giessen, Giessen, Germany., Bergholz A; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Argente Navarro P; Department of Anesthesiology, Perioperative Medicine Research Group, Hospital Universitari i Politécnic La Fe, Valencia, Spain., Azparren Cabezón G; Department of Anesthesia and Pain Management, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Barbero-Espinosa S; Department of Anesthesia and Pain Management, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Diaz-Cambronero O; Department of Anesthesiology, Perioperative Medicine Research Group, Hospital Universitari i Politécnic La Fe, Valencia, Spain., Edinger F; Department of Anesthesiology, Operative Intensive Care and Pain Therapy, Justus-Liebig-University Giessen, Giessen, Germany., García-Gregorio N; Department of Anesthesiology, Perioperative Medicine Research Group, Hospital Universitari i Politécnic La Fe, Valencia, Spain., Habicher M; Department of Anesthesiology, Operative Intensive Care and Pain Therapy, Justus-Liebig-University Giessen, Giessen, Germany., Klinkmann G; Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Centre of Rostock, Rostock, Germany; Fraunhofer Institute for Cell Therapy and Immunology, Department of Extracorporeal Therapy Systems, Rostock, Germany., Koch C; Department of Anesthesiology, Operative Intensive Care and Pain Therapy, Justus-Liebig-University Giessen, Giessen, Germany., Kröker A; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Mencke T; Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Centre of Rostock, Rostock, Germany., Moral García V; Department of Anesthesia and Pain Management, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Zitzmann A; Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Centre of Rostock, Rostock, Germany., Lezius S; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Pepić A; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Sessler DI; Outcomes Research Consortium, Department of Anesthesiology, Cleveland Clinic, Cleveland, OH, USA; Outcomes Research Consortium, Cleveland, OH, USA., Sander M; Department of Anesthesiology, Operative Intensive Care and Pain Therapy, Justus-Liebig-University Giessen, Giessen, Germany., Haas SA; Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Centre of Rostock, Rostock, Germany., Reuter DA; Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Centre of Rostock, Rostock, Germany., Saugel B; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Outcomes Research Consortium, Cleveland, OH, USA. Electronic address: bernd.saugel@gmx.de.
Source: British journal of anaesthesia [Br J Anaesth] 2024 Aug; Vol. 133 (2), pp. 277-287. Date of Electronic Publication: 2024 May 26.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 0372541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-6771 (Electronic) Linking ISSN: 00070912 NLM ISO Abbreviation: Br J Anaesth Subsets: MEDLINE
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  Data: Cardiac index-guided therapy to maintain optimised postinduction cardiac index in high-risk patients having major open abdominal surgery: the multicentre randomised iPEGASUS trial.
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  Data: <searchLink fieldCode="AU" term="%22Funcke+S%22">Funcke S</searchLink>; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidt+G%22">Schmidt G</searchLink>; Department of Anesthesiology, Operative Intensive Care and Pain Therapy, Justus-Liebig-University Giessen, Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22Bergholz+A%22">Bergholz A</searchLink>; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Argente+Navarro+P%22">Argente Navarro P</searchLink>; Department of Anesthesiology, Perioperative Medicine Research Group, Hospital Universitari i Politécnic La Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Azparren+Cabezón+G%22">Azparren Cabezón G</searchLink>; Department of Anesthesia and Pain Management, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Barbero-Espinosa+S%22">Barbero-Espinosa S</searchLink>; Department of Anesthesia and Pain Management, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Diaz-Cambronero+O%22">Diaz-Cambronero O</searchLink>; Department of Anesthesiology, Perioperative Medicine Research Group, Hospital Universitari i Politécnic La Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Edinger+F%22">Edinger F</searchLink>; Department of Anesthesiology, Operative Intensive Care and Pain Therapy, Justus-Liebig-University Giessen, Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22García-Gregorio+N%22">García-Gregorio N</searchLink>; Department of Anesthesiology, Perioperative Medicine Research Group, Hospital Universitari i Politécnic La Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Habicher+M%22">Habicher M</searchLink>; Department of Anesthesiology, Operative Intensive Care and Pain Therapy, Justus-Liebig-University Giessen, Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22Klinkmann+G%22">Klinkmann G</searchLink>; Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Centre of Rostock, Rostock, Germany; Fraunhofer Institute for Cell Therapy and Immunology, Department of Extracorporeal Therapy Systems, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Koch+C%22">Koch C</searchLink>; Department of Anesthesiology, Operative Intensive Care and Pain Therapy, Justus-Liebig-University Giessen, Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22Kröker+A%22">Kröker A</searchLink>; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Mencke+T%22">Mencke T</searchLink>; Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Centre of Rostock, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Moral+García+V%22">Moral García V</searchLink>; Department of Anesthesia and Pain Management, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Zitzmann+A%22">Zitzmann A</searchLink>; Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Centre of Rostock, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Lezius+S%22">Lezius S</searchLink>; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Pepić+A%22">Pepić A</searchLink>; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sessler+DI%22">Sessler DI</searchLink>; Outcomes Research Consortium, Department of Anesthesiology, Cleveland Clinic, Cleveland, OH, USA; Outcomes Research Consortium, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Sander+M%22">Sander M</searchLink>; Department of Anesthesiology, Operative Intensive Care and Pain Therapy, Justus-Liebig-University Giessen, Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22Haas+SA%22">Haas SA</searchLink>; Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Centre of Rostock, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Reuter+DA%22">Reuter DA</searchLink>; Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Medical Centre of Rostock, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Saugel+B%22">Saugel B</searchLink>; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Outcomes Research Consortium, Cleveland, OH, USA. Electronic address: bernd.saugel@gmx.de.
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  Data: <searchLink fieldCode="JN" term="%220372541%22">British journal of anaesthesia</searchLink> [Br J Anaesth] 2024 Aug; Vol. 133 (2), pp. 277-287. <i>Date of Electronic Publication: </i>2024 May 26.
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