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Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice.

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Title: Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice.
Authors: En A; Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Graduate School of Nanobioscience, Yokohama City University, Yokohama, Kanagawa 236-0027, Japan., Bogireddi H; Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Thomas B; Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Stutzman AV; Department of Pediatrics, the University of Chicago, Chicago, IL 60637, USA., Ikegami S; Department of Pediatrics, the University of Chicago, Chicago, IL 60637, USA., LaForest B; Department of Pediatrics, the University of Chicago, Chicago, IL 60637, USA., Almakki O; Department of Pediatrics, the University of Chicago, Chicago, IL 60637, USA., Pytel P; Department of Pathology, the University of Chicago, Chicago, IL 60637, USA., Moskowitz IP; Department of Pediatrics, the University of Chicago, Chicago, IL 60637, USA; Department of Pathology, the University of Chicago, Chicago, IL 60637, USA; Department of Human Genetics, the University of Chicago, Chicago, IL 60637, USA., Ikegami K; Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA. Electronic address: kohta.ikegami@cchmc.org.
Source: Cell reports [Cell Rep] 2024 Jun 25; Vol. 43 (6), pp. 114284. Date of Electronic Publication: 2024 May 29.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice.
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  Data: <searchLink fieldCode="AU" term="%22En+A%22">En A</searchLink>; Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Graduate School of Nanobioscience, Yokohama City University, Yokohama, Kanagawa 236-0027, Japan.<br /><searchLink fieldCode="AU" term="%22Bogireddi+H%22">Bogireddi H</searchLink>; Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+B%22">Thomas B</searchLink>; Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22Stutzman+AV%22">Stutzman AV</searchLink>; Department of Pediatrics, the University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Ikegami+S%22">Ikegami S</searchLink>; Department of Pediatrics, the University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22LaForest+B%22">LaForest B</searchLink>; Department of Pediatrics, the University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Almakki+O%22">Almakki O</searchLink>; Department of Pediatrics, the University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Pytel+P%22">Pytel P</searchLink>; Department of Pathology, the University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Moskowitz+IP%22">Moskowitz IP</searchLink>; Department of Pediatrics, the University of Chicago, Chicago, IL 60637, USA; Department of Pathology, the University of Chicago, Chicago, IL 60637, USA; Department of Human Genetics, the University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Ikegami+K%22">Ikegami K</searchLink>; Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA. Electronic address: kohta.ikegami@cchmc.org.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2024 Jun 25; Vol. 43 (6), pp. 114284. <i>Date of Electronic Publication: </i>2024 May 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101573691 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2211-1247 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Rep <i>Subsets: </i>MEDLINE
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              Text: 2024 Jun 25
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