View in EDS

Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule.

Saved in:
Bibliographic Details
Title: Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule.
Authors: Kelly LM; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France., Rutter JC; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Lin KH; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Ling F; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France., Duchmann M; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France., Latour E; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France., Arang N; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA., Pasquer H; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France., Ho Nhat D; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France., Charles J; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France., Killarney ST; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Ang HX; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Namor F; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France., Culeux C; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France., Lombard B; Curie Institute, Mass Spectrometry and Proteomics Facility, PSL Research University, Paris, France., Loew D; Curie Institute, Mass Spectrometry and Proteomics Facility, PSL Research University, Paris, France., Swaney DL; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.; Gladstone Institutes, San Francisco, California, USA., Krogan NJ; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.; Gladstone Institutes, San Francisco, California, USA., Brunel L; IBMM, University of Montpellier, CNRS, ENSCM, Montpellier, France., Carretero É; IBMM, University of Montpellier, CNRS, ENSCM, Montpellier, France., Verdié P; IBMM, University of Montpellier, CNRS, ENSCM, Montpellier, France., Amblard M; IBMM, University of Montpellier, CNRS, ENSCM, Montpellier, France., Fodil S; Department of Hematology and Immunology, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France., Huynh T; Department of Hematology and Immunology, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France., Sebert M; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.; Department of Hematology and Immunology, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France., Adès L; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.; Department of Hematology and Immunology, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France., Raffoux E; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.; Department of Hematology and Immunology, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France., Fenouille N; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France., Itzykson R; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.; Department of Hematology and Immunology, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France., Lobry C; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France., Benajiba L; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.; Clinical Investigation Center, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France., Forget A; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA., Martin AR; IBMM, University of Montpellier, CNRS, ENSCM, Montpellier, France. anthony.martin@umontpellier.fr., Wood KC; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA. kris.wood@duke.edu., Puissant A; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France. alexandre.puissant@inserm.fr.
Source: Nature cancer [Nat Cancer] 2024 Jul; Vol. 5 (7), pp. 1082-1101. Date of Electronic Publication: 2024 May 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 38816660
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Kelly+LM%22">Kelly LM</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Rutter+JC%22">Rutter JC</searchLink>; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Lin+KH%22">Lin KH</searchLink>; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ling+F%22">Ling F</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Duchmann+M%22">Duchmann M</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Latour+E%22">Latour E</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Arang+N%22">Arang N</searchLink>; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pasquer+H%22">Pasquer H</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Ho+Nhat+D%22">Ho Nhat D</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Charles+J%22">Charles J</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Killarney+ST%22">Killarney ST</searchLink>; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ang+HX%22">Ang HX</searchLink>; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Namor+F%22">Namor F</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Culeux+C%22">Culeux C</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lombard+B%22">Lombard B</searchLink>; Curie Institute, Mass Spectrometry and Proteomics Facility, PSL Research University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Loew+D%22">Loew D</searchLink>; Curie Institute, Mass Spectrometry and Proteomics Facility, PSL Research University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Swaney+DL%22">Swaney DL</searchLink>; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.; Gladstone Institutes, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Krogan+NJ%22">Krogan NJ</searchLink>; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.; Gladstone Institutes, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Brunel+L%22">Brunel L</searchLink>; IBMM, University of Montpellier, CNRS, ENSCM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Carretero+É%22">Carretero É</searchLink>; IBMM, University of Montpellier, CNRS, ENSCM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Verdié+P%22">Verdié P</searchLink>; IBMM, University of Montpellier, CNRS, ENSCM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Amblard+M%22">Amblard M</searchLink>; IBMM, University of Montpellier, CNRS, ENSCM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Fodil+S%22">Fodil S</searchLink>; Department of Hematology and Immunology, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Huynh+T%22">Huynh T</searchLink>; Department of Hematology and Immunology, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Sebert+M%22">Sebert M</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.; Department of Hematology and Immunology, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Adès+L%22">Adès L</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.; Department of Hematology and Immunology, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Raffoux+E%22">Raffoux E</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.; Department of Hematology and Immunology, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Fenouille+N%22">Fenouille N</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Itzykson+R%22">Itzykson R</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.; Department of Hematology and Immunology, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lobry+C%22">Lobry C</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Benajiba+L%22">Benajiba L</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France.; Clinical Investigation Center, Saint-Louis Hospital, AP-HP, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Forget+A%22">Forget A</searchLink>; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Martin+AR%22">Martin AR</searchLink>; IBMM, University of Montpellier, CNRS, ENSCM, Montpellier, France. anthony.martin@umontpellier.fr.<br /><searchLink fieldCode="AU" term="%22Wood+KC%22">Wood KC</searchLink>; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA. kris.wood@duke.edu.<br /><searchLink fieldCode="AU" term="%22Puissant+A%22">Puissant A</searchLink>; INSERM UMR 944, IRSL, Saint-Louis Hospital, Paris Cité University, Paris, France. alexandre.puissant@inserm.fr.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101761119%22">Nature cancer</searchLink> [Nat Cancer] 2024 Jul; Vol. 5 (7), pp. 1082-1101. <i>Date of Electronic Publication: </i>2024 May 30.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101761119 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2662-1347 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226621347%22">26621347 </searchLink><i>NLM ISO Abbreviation: </i>Nat Cancer <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=38816660
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s43018-024-00782-5
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1082
    Titles:
      – TitleFull: Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Kelly LM
      – PersonEntity:
          Name:
            NameFull: Rutter JC
      – PersonEntity:
          Name:
            NameFull: Lin KH
      – PersonEntity:
          Name:
            NameFull: Ling F
      – PersonEntity:
          Name:
            NameFull: Duchmann M
      – PersonEntity:
          Name:
            NameFull: Latour E
      – PersonEntity:
          Name:
            NameFull: Arang N
      – PersonEntity:
          Name:
            NameFull: Pasquer H
      – PersonEntity:
          Name:
            NameFull: Ho Nhat D
      – PersonEntity:
          Name:
            NameFull: Charles J
      – PersonEntity:
          Name:
            NameFull: Killarney ST
      – PersonEntity:
          Name:
            NameFull: Ang HX
      – PersonEntity:
          Name:
            NameFull: Namor F
      – PersonEntity:
          Name:
            NameFull: Culeux C
      – PersonEntity:
          Name:
            NameFull: Lombard B
      – PersonEntity:
          Name:
            NameFull: Loew D
      – PersonEntity:
          Name:
            NameFull: Swaney DL
      – PersonEntity:
          Name:
            NameFull: Krogan NJ
      – PersonEntity:
          Name:
            NameFull: Brunel L
      – PersonEntity:
          Name:
            NameFull: Carretero É
      – PersonEntity:
          Name:
            NameFull: Verdié P
      – PersonEntity:
          Name:
            NameFull: Amblard M
      – PersonEntity:
          Name:
            NameFull: Fodil S
      – PersonEntity:
          Name:
            NameFull: Huynh T
      – PersonEntity:
          Name:
            NameFull: Sebert M
      – PersonEntity:
          Name:
            NameFull: Adès L
      – PersonEntity:
          Name:
            NameFull: Raffoux E
      – PersonEntity:
          Name:
            NameFull: Fenouille N
      – PersonEntity:
          Name:
            NameFull: Itzykson R
      – PersonEntity:
          Name:
            NameFull: Lobry C
      – PersonEntity:
          Name:
            NameFull: Benajiba L
      – PersonEntity:
          Name:
            NameFull: Forget A
      – PersonEntity:
          Name:
            NameFull: Martin AR
      – PersonEntity:
          Name:
            NameFull: Wood KC
      – PersonEntity:
          Name:
            NameFull: Puissant A
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: 2024 Jul
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 2662-1347
          Numbering:
            – Type: volume
              Value: 5
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Nature cancer
              Type: main
ResultId 1