Impact of CYP2C19 metabolizer status on esophageal mucosal inflammation, acid exposure, and motility among patients on chronic proton-pump inhibitor therapy with refractory symptoms of gastroesophageal reflux disease.

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Title: Impact of CYP2C19 metabolizer status on esophageal mucosal inflammation, acid exposure, and motility among patients on chronic proton-pump inhibitor therapy with refractory symptoms of gastroesophageal reflux disease.
Authors: Tai CC; Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON N6A 5C1, Canada., Medwid S; Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON N6A 5C1, Canada.; Division of Clinical Pharmacology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON N6A 5C1, Canada., Mclntosh K; Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON N6A 5C1, Canada.; Division of Gastroenterology, Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON N6A 5C1, Canada., Chande N; Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON N6A 5C1, Canada.; Division of Gastroenterology, Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON N6A 5C1, Canada., Kim RB; Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON N6A 5C1, Canada.; Division of Clinical Pharmacology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON N6A 5C1, Canada., Gregor J; Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON N6A 5C1, Canada.; Division of Gastroenterology, Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON N6A 5C1, Canada.
Source: Journal of the Canadian Association of Gastroenterology [J Can Assoc Gastroenterol] 2024 Feb 10; Vol. 7 (3), pp. 238-245. Date of Electronic Publication: 2024 Feb 10 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101738684 Publication Model: eCollection Cited Medium: Internet ISSN: 2515-2092 (Electronic) Linking ISSN: 25152084 NLM ISO Abbreviation: J Can Assoc Gastroenterol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2515-2092
DOI:10.1093/jcag/gwae005