Single molecule array measures of LRRK2 kinase activity in serum link Parkinson's disease severity to peripheral inflammation.

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Title: Single molecule array measures of LRRK2 kinase activity in serum link Parkinson's disease severity to peripheral inflammation.
Authors: Yuan Y; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Li H; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Sreeram K; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Malankhanova T; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Boddu R; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Strader S; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Chang A; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Bryant N; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Yacoubian TA; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Standaert DG; Department of Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI, USA., Erb M; Department of Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI, USA., Moore DJ; Department of Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI, USA., Sanders LH; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Neurology, Duke University, Durham, NC, USA.; Department of Pathology, Duke University, Durham, NC, USA., Lutz MW; Department of Neurology, Duke University, Durham, NC, USA.; Department of Pathology, Duke University, Durham, NC, USA., Velmeshev D; Department of Neurobiology, Duke University, Durham, NC, USA., West AB; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA. Andrew.West@Duke.edu.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA. Andrew.West@Duke.edu.; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA. Andrew.West@Duke.edu.; Department of Neurology, Duke University, Durham, NC, USA. Andrew.West@Duke.edu.; Department of Neurobiology, Duke University, Durham, NC, USA. Andrew.West@Duke.edu.
Source: Molecular neurodegeneration [Mol Neurodegener] 2024 Jun 11; Vol. 19 (1), pp. 47. Date of Electronic Publication: 2024 Jun 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1750-1326
DOI:10.1186/s13024-024-00738-4