Prediction of the liver safety profile of a first-in-class myeloperoxidase inhibitor using quantitative systems toxicology modeling.

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Title: Prediction of the liver safety profile of a first-in-class myeloperoxidase inhibitor using quantitative systems toxicology modeling.
Authors: Woodhead JL; Simulations Plus, Inc., Lancaster, CA, USA., Gebremichael Y; Quantitative Pharmacology, EMD Serono Inc., Raleigh, NC, USA., Macwan J; Simulations Plus, Inc., Lancaster, CA, USA., Qureshi IA; Biohaven Inc., New Haven, CT, USA., Bertz R; Biohaven Inc., New Haven, CT, USA., Wirtz V; Biohaven Inc., New Haven, CT, USA., Howell BA; Simulations Plus, Inc., Lancaster, CA, USA.
Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2024 Jul; Vol. 54 (7), pp. 401-410. Date of Electronic Publication: 2024 Aug 21.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1366-5928
DOI:10.1080/00498254.2024.2361027