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Prediction of the liver safety profile of a first-in-class myeloperoxidase inhibitor using quantitative systems toxicology modeling.

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Title: Prediction of the liver safety profile of a first-in-class myeloperoxidase inhibitor using quantitative systems toxicology modeling.
Authors: Woodhead JL; Simulations Plus, Inc., Lancaster, CA, USA., Gebremichael Y; Quantitative Pharmacology, EMD Serono Inc., Raleigh, NC, USA., Macwan J; Simulations Plus, Inc., Lancaster, CA, USA., Qureshi IA; Biohaven Inc., New Haven, CT, USA., Bertz R; Biohaven Inc., New Haven, CT, USA., Wirtz V; Biohaven Inc., New Haven, CT, USA., Howell BA; Simulations Plus, Inc., Lancaster, CA, USA.
Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2024 Jul; Vol. 54 (7), pp. 401-410. Date of Electronic Publication: 2024 Aug 21.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Prediction of the liver safety profile of a first-in-class myeloperoxidase inhibitor using quantitative systems toxicology modeling.
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  Data: <searchLink fieldCode="AU" term="%22Woodhead+JL%22">Woodhead JL</searchLink>; Simulations Plus, Inc., Lancaster, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gebremichael+Y%22">Gebremichael Y</searchLink>; Quantitative Pharmacology, EMD Serono Inc., Raleigh, NC, USA.<br /><searchLink fieldCode="AU" term="%22Macwan+J%22">Macwan J</searchLink>; Simulations Plus, Inc., Lancaster, CA, USA.<br /><searchLink fieldCode="AU" term="%22Qureshi+IA%22">Qureshi IA</searchLink>; Biohaven Inc., New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Bertz+R%22">Bertz R</searchLink>; Biohaven Inc., New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Wirtz+V%22">Wirtz V</searchLink>; Biohaven Inc., New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Howell+BA%22">Howell BA</searchLink>; Simulations Plus, Inc., Lancaster, CA, USA.
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  Data: <searchLink fieldCode="JN" term="%221306665%22">Xenobiotica; the fate of foreign compounds in biological systems</searchLink> [Xenobiotica] 2024 Jul; Vol. 54 (7), pp. 401-410. <i>Date of Electronic Publication: </i>2024 Aug 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Informa+Healthcare%22">Informa Healthcare </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>1306665 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1366-5928 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200498254%22">00498254 </searchLink><i>NLM ISO Abbreviation: </i>Xenobiotica <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1080/00498254.2024.2361027
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      – Code: eng
        Text: English
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        StartPage: 401
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      – TitleFull: Prediction of the liver safety profile of a first-in-class myeloperoxidase inhibitor using quantitative systems toxicology modeling.
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              Text: 2024 Jul
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              Value: 54
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            – TitleFull: Xenobiotica; the fate of foreign compounds in biological systems
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