The PDE4 inhibitor apremilast modulates ethanol responses in Gabrb1-S409A knock-in mice via PKA-dependent and independent mechanisms.

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Title: The PDE4 inhibitor apremilast modulates ethanol responses in Gabrb1-S409A knock-in mice via PKA-dependent and independent mechanisms.
Authors: Blednov YA; Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, TX, 78712, USA., Shawlot W; Center for Biomedical Research Support, Mouse Genetic Engineering Facility, The University of Texas at Austin, Austin, TX, 78712, USA., Homanics GE; Departments of Anesthesiology & Perioperative Medicine, Neurobiology, and Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Osterndorff-Kahanek EA; Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, TX, 78712, USA., Mason S; Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, TX, 78712, USA., Mayfield J; Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, TX, 78712, USA., Smalley JL; Department of Neuroscience, Tufts University School of Medicine, Boston, MA, 02111, USA., Moss SJ; Department of Neuroscience, Tufts University School of Medicine, Boston, MA, 02111, USA., Messing RO; Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, TX, 78712, USA; Department of Neuroscience, The University of Texas at Austin, Austin, TX, 78712, USA; Department of Neurology, Dell Medical School, The University of Texas at Austin, Austin, TX, 78712, USA. Electronic address: romessing@austin.utexas.edu.
Source: Neuropharmacology [Neuropharmacology] 2024 Oct 01; Vol. 257, pp. 110035. Date of Electronic Publication: 2024 Jun 13.
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-7064
DOI:10.1016/j.neuropharm.2024.110035