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Metformin Mitigates Sepsis-Induced Acute Lung Injury and Inflammation in Young Mice by Suppressing the S100A8/A9-NLRP3-IL-1β Signaling Pathway.

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Title: Metformin Mitigates Sepsis-Induced Acute Lung Injury and Inflammation in Young Mice by Suppressing the S100A8/A9-NLRP3-IL-1β Signaling Pathway.
Authors: Fan SY; The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, People's Republic of China., Zhao ZC; The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, People's Republic of China., Liu XL; The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, People's Republic of China., Peng YG; The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, People's Republic of China., Zhu HM; The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, People's Republic of China., Yan SF; Department of Emergency, Institute of Emergency Medicine, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan, 410005, People's Republic of China., Liu YJ; Department of Emergency, Institute of Emergency Medicine, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan, 410005, People's Republic of China., Xie Q; Department of Emergency, Institute of Emergency Medicine, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan, 410005, People's Republic of China., Jiang Y; Department of Emergency, Institute of Emergency Medicine, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan, 410005, People's Republic of China., Zeng SZ; The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, People's Republic of China.
Source: Journal of inflammation research [J Inflamm Res] 2024 Jun 12; Vol. 17, pp. 3785-3799. Date of Electronic Publication: 2024 Jun 12 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Dove Medical Press Country of Publication: New Zealand NLM ID: 101512684 Publication Model: eCollection Cited Medium: Print ISSN: 1178-7031 (Print) Linking ISSN: 11787031 NLM ISO Abbreviation: J Inflamm Res Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1178-7031
DOI:10.2147/JIR.S460413