Gliovascular transcriptional perturbations in Alzheimer's disease reveal molecular mechanisms of blood brain barrier dysfunction.
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| Title: | Gliovascular transcriptional perturbations in Alzheimer's disease reveal molecular mechanisms of blood brain barrier dysfunction. |
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| Authors: | İş Ö; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Wang X; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Reddy JS; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Min Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Yilmaz E; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA., Bhattarai P; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA., Patel T; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Bergman J; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Quicksall Z; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Heckman MG; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Tutor-New FQ; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Can Demirdogen B; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Department of Biomedical Engineering, TOBB University of Economics and Technology, Ankara, Turkey., White L; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Koga S; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Krause V; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Inoue Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Kanekiyo T; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Cosacak MI; German Center for Neurodegenerative Diseases (DZNE) within Helmholtz Association, Dresden, Germany., Nelson N; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA., Lee AJ; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA.; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA., Vardarajan B; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA.; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA., Mayeux R; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA.; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA., Kouri N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Deniz K; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Carnwath T; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Oatman SR; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Lewis-Tuffin LJ; Mayo Clinic Florida Cytometry and Cell Imaging Laboratory, Mayo Clinic, Jacksonville, FL, USA., Nguyen T; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Carrasquillo MM; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Graff-Radford J; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Petersen RC; Department of Neurology, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Alzheimer's Disease Research Center, Rochester, MN, USA., Jr Jack CR; Mayo Clinic, Radiology, Rochester, MN, USA., Kantarci K; Mayo Clinic Alzheimer's Disease Research Center, Rochester, MN, USA., Murray ME; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Nho K; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Alzheimer's Disease Research Center, Indiana University School of Medicine, Indianapolis, IN, USA., Saykin AJ; Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Alzheimer's Disease Research Center, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Kizil C; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA.; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA., Allen M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Ertekin-Taner N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. taner.nilufer@mayo.edu.; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA. taner.nilufer@mayo.edu. |
| Corporate Authors: | Alzheimer’s Disease Neuroimaging Initiative |
| Source: | Nature communications [Nat Commun] 2024 Jun 20; Vol. 15 (1), pp. 4758. Date of Electronic Publication: 2024 Jun 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-024-48926-6 |
