Is the Hedgehog Pathway Involved in the Pathophysiology of Schizophrenia? A Systematic Review of Current Evidence of Neural Molecular Correlates and Perspectives on Drug Development.

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Title: Is the Hedgehog Pathway Involved in the Pathophysiology of Schizophrenia? A Systematic Review of Current Evidence of Neural Molecular Correlates and Perspectives on Drug Development.
Authors: Del Casale A; Department of Dynamic and Clinical Psychology and Health Studies, Faculty of Medicine and Psychology, Sapienza University of Rome, 00185 Rome, Italy.; Unit of Psychiatry, Emergency and Admissions Department, Sant'Andrea University Hospital, 00189 Rome, Italy., Modesti MN; Department of Psychology, Faculty of Medicine and Psychology, Sapienza University of Rome, 00185 Rome, Italy.; Unit of Psychiatry, Mental Health Department, Santissimo Gonfalone Hospital, Local Health Service Roma 5, Monterotondo, 00015 Rome, Italy., Gentile G; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University, 00189 Rome, Italy.; Unit of Laboratory and Advanced Molecular Diagnostics, Sant'Andrea University Hospital, 00189 Rome, Italy., Guariglia C; Department of Psychology, Faculty of Medicine and Psychology, Sapienza University of Rome, 00185 Rome, Italy.; Cognitive and Motor Rehabilitation and Neuroimaging Unit, Scientific Institute for Research, Hospitalization and Healthcare Fondazione Santa Lucia, 00179 Rome, Italy., Ferracuti S; Department of Human Neuroscience, Faculty of Medicine and Dentistry, Sapienza University of Rome, 00185 Rome, Italy.; Unit of Risk Management, Sant'Andrea University Hospital, 00189 Rome, Italy., Simmaco M; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University, 00189 Rome, Italy.; Unit of Laboratory and Advanced Molecular Diagnostics, Sant'Andrea University Hospital, 00189 Rome, Italy., Borro M; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University, 00189 Rome, Italy.; Unit of Laboratory and Advanced Molecular Diagnostics, Sant'Andrea University Hospital, 00189 Rome, Italy.
Source: Current issues in molecular biology [Curr Issues Mol Biol] 2024 May 27; Vol. 46 (6), pp. 5322-5336. Date of Electronic Publication: 2024 May 27.
Publication Type: Journal Article; Review
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100931761 Publication Model: Electronic Cited Medium: Internet ISSN: 1467-3045 (Electronic) Linking ISSN: 14673037 NLM ISO Abbreviation: Curr Issues Mol Biol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1467-3045
DOI:10.3390/cimb46060318