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A novel controlled metabolic accelerator for the treatment of obesity-related heart failure with preserved ejection fraction: Rationale and design of the Phase 2a HuMAIN trial.

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Title: A novel controlled metabolic accelerator for the treatment of obesity-related heart failure with preserved ejection fraction: Rationale and design of the Phase 2a HuMAIN trial.
Authors: Kitzman DW; Section on Geriatrics and Gerontology, Department of Cardiovascular Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Lewis GD; Department of Medicine, Massachusetts General Brigham, Boston, MA, USA., Pandey A; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA., Borlaug BA; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Sauer AJ; Department of Cardiology, Saint Luke's Mid America Heart Institute, Kansas City, MO, USA., Litwin SE; Division of Cardiology, Medical University of South Carolina, Charleston, SC, USA.; Division of Cardiology, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC, USA., Sharma K; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD, USA., Jorkasky DK; Devon, PA, USA., Khan S; Rivus Pharmaceuticals, Charlottesville, VA, USA., Shah SJ; Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Source: European journal of heart failure [Eur J Heart Fail] 2024 Sep; Vol. 26 (9), pp. 2013-2024. Date of Electronic Publication: 2024 Jun 26.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 100887595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0844 (Electronic) Linking ISSN: 13889842 NLM ISO Abbreviation: Eur J Heart Fail Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1879-0844
DOI:10.1002/ejhf.3305