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A novel controlled metabolic accelerator for the treatment of obesity-related heart failure with preserved ejection fraction: Rationale and design of the Phase 2a HuMAIN trial.

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Title: A novel controlled metabolic accelerator for the treatment of obesity-related heart failure with preserved ejection fraction: Rationale and design of the Phase 2a HuMAIN trial.
Authors: Kitzman DW; Section on Geriatrics and Gerontology, Department of Cardiovascular Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Lewis GD; Department of Medicine, Massachusetts General Brigham, Boston, MA, USA., Pandey A; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA., Borlaug BA; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Sauer AJ; Department of Cardiology, Saint Luke's Mid America Heart Institute, Kansas City, MO, USA., Litwin SE; Division of Cardiology, Medical University of South Carolina, Charleston, SC, USA.; Division of Cardiology, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC, USA., Sharma K; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD, USA., Jorkasky DK; Devon, PA, USA., Khan S; Rivus Pharmaceuticals, Charlottesville, VA, USA., Shah SJ; Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Source: European journal of heart failure [Eur J Heart Fail] 2024 Sep; Vol. 26 (9), pp. 2013-2024. Date of Electronic Publication: 2024 Jun 26.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 100887595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0844 (Electronic) Linking ISSN: 13889842 NLM ISO Abbreviation: Eur J Heart Fail Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A novel controlled metabolic accelerator for the treatment of obesity-related heart failure with preserved ejection fraction: Rationale and design of the Phase 2a HuMAIN trial.
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  Data: <searchLink fieldCode="AU" term="%22Kitzman+DW%22">Kitzman DW</searchLink>; Section on Geriatrics and Gerontology, Department of Cardiovascular Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+GD%22">Lewis GD</searchLink>; Department of Medicine, Massachusetts General Brigham, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pandey+A%22">Pandey A</searchLink>; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Borlaug+BA%22">Borlaug BA</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Sauer+AJ%22">Sauer AJ</searchLink>; Department of Cardiology, Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Litwin+SE%22">Litwin SE</searchLink>; Division of Cardiology, Medical University of South Carolina, Charleston, SC, USA.; Division of Cardiology, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC, USA.<br /><searchLink fieldCode="AU" term="%22Sharma+K%22">Sharma K</searchLink>; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Jorkasky+DK%22">Jorkasky DK</searchLink>; Devon, PA, USA.<br /><searchLink fieldCode="AU" term="%22Khan+S%22">Khan S</searchLink>; Rivus Pharmaceuticals, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Shah+SJ%22">Shah SJ</searchLink>; Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
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  Data: <searchLink fieldCode="JN" term="%22100887595%22">European journal of heart failure</searchLink> [Eur J Heart Fail] 2024 Sep; Vol. 26 (9), pp. 2013-2024. <i>Date of Electronic Publication: </i>2024 Jun 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100887595 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0844 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213889842%22">13889842 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Heart Fail <i>Subsets: </i>MEDLINE
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        Value: 10.1002/ejhf.3305
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        Text: English
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        StartPage: 2013
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      – TitleFull: A novel controlled metabolic accelerator for the treatment of obesity-related heart failure with preserved ejection fraction: Rationale and design of the Phase 2a HuMAIN trial.
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              Text: 2024 Sep
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