KCa channel targeting impairs DNA repair and invasiveness of patient-derived glioblastoma stem cells in culture and orthotopic mouse xenografts which only in part is predictable by KCa expression levels.
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| Title: | K |
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| Authors: | Ganser K; Department of Radiation Oncology, University Hospital of Tübingen, Tübingen, Germany., Stransky N; Department of Radiation Oncology, University Hospital of Tübingen, Tübingen, Germany.; Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany., Abed T; Department of Radiation Oncology, University Hospital of Tübingen, Tübingen, Germany., Quintanilla-Martinez L; Institute of Pathology and Neuropathology, Comprehensive Cancer Center, Eberhard Karls University of Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180), Image-Guided and Functionally Instructed Tumor Therapies, Eberhard Karls University, Tuebingen, Germany., Gonzalez-Menendez I; Institute of Pathology and Neuropathology, Comprehensive Cancer Center, Eberhard Karls University of Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180), Image-Guided and Functionally Instructed Tumor Therapies, Eberhard Karls University, Tuebingen, Germany., Naumann U; Molecular Neurooncology, Hertie Institute for Clinical Brain Research and Center Neurology, University of Tübingen, Tübingen, Germany., Koch P; Department of Pharmaceutical/Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Regensburg, Germany., Krueger M; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, University of Tübingen, Tübingen, Germany., Ruth P; Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany., Huber SM; Department of Radiation Oncology, University Hospital of Tübingen, Tübingen, Germany., Eckert F; Department of Radiation Oncology, University Hospital of Tübingen, Tübingen, Germany.; Department of Radiation Oncology, Medical University Vienna, AKH, Comprehensive Cancer Center, Vienna, Austria. |
| Source: | International journal of cancer [Int J Cancer] 2024 Nov 15; Vol. 155 (10), pp. 1886-1901. Date of Electronic Publication: 2024 Jun 27. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1097-0215 |
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| DOI: | 10.1002/ijc.35064 |
