Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease.

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Title: Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease.
Authors: Vogelgsang J; Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA., Hansen N; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany., Stark M; German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Center, Bonn, Germany., Wagner M; German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Center, Bonn, Germany., Klafki H; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany., Morgado BM; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany., Jahn-Brodmann A; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany., Schott B; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany., Esselmann H; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany., Bauer C; MicroDiscivery GmbH, Berlin, Germany., Schuchhardt J; MicroDiscivery GmbH, Berlin, Germany., Kleineidam L; German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Center, Bonn, Germany., Wolfsgruber S; German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Center, Bonn, Germany., Peters O; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany., Schneider LS; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany., Wang X; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany., Menne F; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Predemtec AG, Rudower Chausee 29, Berlin, Germany., Priller J; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany.; School of Medicine, Department of Psychiatry and Psychotherapy, Technical University of Munich, Munich, Germany.; University of Edinburgh and UK DRI, Edinburgh, UK., Spruth E; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany., Altenstein S; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany., Lohse A; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany., Schneider A; German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Center, Bonn, Germany., Fliessbach K; German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Center, Bonn, Germany., Vogt I; German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany., Bartels C; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany., Jessen F; German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.; Department of Psychiatry, University of Cologne, Medical Faculty, Cologne, Germany.; Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany., Rostamzadeh A; Department of Psychiatry, University of Cologne, Medical Faculty, Cologne, Germany., Duezel E; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany., Glanz W; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany., Incesoy E; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany.; Department for Psychiatry and Psychotherapy, University Clinic Magdeburg, Magdeburg, Germany., Butryn M; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany., Buerger K; German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Janowitz D; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Ewers M; German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Perneczky R; German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy) Munich, Munich, Germany.; Ageing Epidemiology Research Unit (AGE), School of Public Health, Imperial College London, South Kensington, London, UK., Rauchmann B; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Broomhall, Sheffield, UK.; Department of Neuroradiology, University Hospital LMU, Marchioninistrassee, Munich, Germany., Guersel S; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany., Teipel S; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany., Kilimann I; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany., Goerss D; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany., Laske C; German Center for Neurodegenerative Diseases (DZNE), Tuebingen, Germany.; Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tuebingen, Tuebingen, Germany., Munk M; German Center for Neurodegenerative Diseases (DZNE), Tuebingen, Germany.; Department of Psychiatry and Psychotherapy, University of Tuebingen, Tuebingen, Germany., Sanzenbacher C; German Center for Neurodegenerative Diseases (DZNE), Tuebingen, Germany., Spottke A; German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.; Department of Neurology, University of Bonn, Bonn, Germany., Roy-Kluth N; German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany., Heneka M; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval Esch-sur-Alzette, Luxembourg., Brosseron F; German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany., Ramierez A; German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Center, Bonn, Germany.; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Department of Psychiatry & Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, Texas, USA., Schmid M; German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.; Institute for Medical Biometry, University Hospital Bonn, Bonn, Germany., Wiltfang J; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Goettingen, Germany.; Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, Aveiro, Portugal.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Aug; Vol. 20 (8), pp. 5132-5142. Date of Electronic Publication: 2024 Jun 28.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1552-5279
DOI:10.1002/alz.13909