Preexisting maternal immunity to AAV but not Cas9 impairs in utero gene editing in mice.

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Bibliographic Details
Title: Preexisting maternal immunity to AAV but not Cas9 impairs in utero gene editing in mice.
Authors: Riley JS; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Luks VL; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Berkowitz CL; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Dumitru AM; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Kus NJ; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Dave A; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Menon P; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., De Paepe ME; Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, USA., Jain R; Division of Cardiology, Department of Medicine, and., Li L; Division of Cardiology, Department of Medicine, and., Dugoff L; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Teefey CP; Center for Fetal Diagnosis and Treatment and., Alameh MG; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Zoltick PW; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Peranteau WH; Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Center for Fetal Diagnosis and Treatment and.
Source: The Journal of clinical investigation [J Clin Invest] 2024 May 09; Vol. 134 (12). Date of Electronic Publication: 2024 May 09.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1558-8238
DOI:10.1172/JCI179848